871676-36-7

Basic information

• Product Name: 5-(3-TRIFLUOROMETHYLPHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 5-(3-TRIFLUOROMETHYLPHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYL ESTER;5-[3-(TRIFLUOROMETHYL)PHENYL]-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER
• CAS NO: 871676-36-7
• Molecular Formula: C₁₃H₁₀F₃NO₃
• Molecular Weight: 285.22
• Mol File: 871676-36-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(3-TRIFLUOROMETHYLPHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-TRIFLUOROMETHYLPHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(871676-36-7)
• EPA Substance Registry System: 5-(3-TRIFLUOROMETHYLPHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(871676-36-7)

Safety Data

• Hazardous Substances Data: 871676-36-7(Hazardous Substances Data)

Upstream product

• 705-28-2 1-ethynyl-3-trifluoromethylbenzene 
• 14337-43-0 ethyl 2-chloro-2-(hydroxyimino)acetate 
• 737772-45-1 2,4-dioxo-4-(3-trifluoromethylphenyl)butyric acid ethyl ester 
• 95080-93-6 ethyl chlorooximidoacetate 

Downstream Products

• 1013634-97-3 {5-[3-(trifluoromethyl)phenyl]isoxazol-3-yl}methan-1-ol 
• 1013634-94-0 3-(bromomethyl)-5-[3-(trifluoromethyl)phenyl]isoxazole 

Relevant articles and documents

PIPERIDINE CXCR7 RECEPTOR MODULATORS

The present invention relates to piperidine derivatives of formula (I) wherein Ar1, Ar2, RAr1, R1, R2, and R3 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators.

ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION

Disclosed are novel isoflavone derivatives having the structure of Formula I which are useful as ALDH-2 inhibitors for treating mammals for dependence upon drugs of addiction, for example addiction to dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and alcohol.

THIOPHENE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS

Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufac