873056-09-8

Basic information

• Product Name: N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide
• Synonyms: N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide
• CAS NO: 873056-09-8
• Molecular Weight: 254.233
• Mol File: 873056-09-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide(873056-09-8)
• EPA Substance Registry System: N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide(873056-09-8)

Safety Data

• Hazardous Substances Data: 873056-09-8(Hazardous Substances Data)

Upstream product

• 368-53-6 5-(trifluoromethyl)benzene-1,3-diamine 
• 124-63-0 methanesulfonyl chloride 
• 401-94-5 3-nitro-5-(trifluoromethyl)-phenylamine 
• 618446-51-8 (2R)-2-(((3-nitro-5-(trifluoromethyl)-phenyl)-oxy)-methyl)-pyrrolidine 
• 618446-45-0 N-[3-nitro-5-(trifluoromethyl)phenyl]methanesulfonamide 

Relevant articles and documents

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The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

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New compounds of formula 1 are provided which by virtue of their pharmaceutical activity as PI3-kinase modulators may be used in the therapeutic field for the treatment of inflammatory or allergic diseases. Examples of these include inflammatory and allergic respiratory complaints, inflammatory diseases of the gastro-intestinal tract and motor apparatus, inflammatory and allergic skin diseases, inflammatory eye diseases, diseases of the nasal mucosa, inflammatory or allergic conditions involving autoimmune reactions or inflammations of the kidney.