87363-78-8

Basic information

• Product Name: Tfa-ΔPhe-(L)-Thr-OMe
• CAS NO: 87363-78-8
• Molecular Weight: 374.317
• Mol File: 87363-78-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Tfa-ΔPhe-(L)-Thr-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Tfa-ΔPhe-(L)-Thr-OMe(87363-78-8)
• EPA Substance Registry System: Tfa-ΔPhe-(L)-Thr-OMe(87363-78-8)

Safety Data

• Hazardous Substances Data: 87363-78-8(Hazardous Substances Data)

Upstream product

• 3373-59-9 L-threonine methyl ester 
• 83791-32-6 N-carboxy dehydrophenylalanine anhydride 
• 407-25-0 trifluoroacetic anhydride 
• 74805-42-8 N-carboxy-α-dehydrophenylalanine anhydride 
• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

Dehydrooligopeptides. VII. Convenient Synthesis of Various Dehydrodi- and tripeptide Esters by Using N-Carboxy α-Dehydroamino Acid Anhydride

The one-pot syntheses of N-protected Δ1- and Δ2-dehydrodipeptide esters by the coupling of N-carboxy α-dehydroamino acid anhydride (ΔNCA) with several kinds of C- or N-protected L-α-amino acids are described.In addition, it was found that a similar coupling of ΔNCA with both C- and N-protected α-amino acids also took place to give Δ2-dehydrotripeptide derivatives, involving eight kinds of important C-terminal segments of antrimycins and cirratiomycins.The configurational confirmation of the α-dehydroisoleucine residue of the antibiotics is also discussed.