875-79-6 Usage
Description
1,2-Dimethylindole is an organic compound that serves as a versatile building block and reactant in the synthesis of various organic molecules and pharmaceutical agents.
Uses
Used in Pharmaceutical Industry:
1,2-Dimethylindole is used as a building block for the preparation of 3-functionalized indoles, which are important in the development of pharmaceutical compounds with diverse biological activities.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a building block for the preparation of carbazoles, a group of nitrogen-containing heterocyclic organic compounds with potential applications in various fields.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a building block for the preparation of cyanoindoles, which are valuable intermediates in the synthesis of various organic compounds.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a reactant for the preparation of trifluoromethylindoles, which are important intermediates in the synthesis of pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
1,2-Dimethylindole is used as a reactant for the preparation of potent antihyperlipidemic agents, which are compounds that help in reducing high levels of lipids in the blood.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a building block in iso-Nazarov or Nazarov cyclizations, which are important reactions in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
1,2-Dimethylindole is used as a reactant for the preparation of GSK-3 inhibitors, which are compounds that target glycogen synthase kinase-3 and have potential applications in the treatment of various diseases.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a building block for the preparation of carboxyindoles, which are valuable intermediates in the synthesis of various organic compounds.
Used in Agriculture:
1,2-Dimethylindole is used as a reactant for the preparation of plant growth promoters, which are compounds that enhance plant growth and development.
Used in Organic Synthesis:
1,2-Dimethylindole is used as a reactant for the preparation of tryptophan derivatives, which are important intermediates in the synthesis of various organic compounds and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 875-79-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 875-79:
(5*8)+(4*7)+(3*5)+(2*7)+(1*9)=106
106 % 10 = 6
So 875-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N/c1-8-7-9-5-3-4-6-10(9)11(8)2/h3-7H,1-2H3
875-79-6Relevant articles and documents
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van Duuren
, p. 2954,2960 (1961)
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Asymmetric transfer hydrogenation of heterocycle-containing acetophenone derivatives using N-functionalised [(benzene)Ru(II)(TsDPEN)] complexes
Barrios-Rivera, Jonathan,Xu, Yingjian,Clarkson, Guy J.,Wills, Martin
supporting information, (2021/12/02)
The application of enantiomerically-pure ruthenium(II) catalysts containing N - functionalised TsDPEN ligand to the asymmetric transfer hydrogenation of 15 examples of α-heterocyclic acetophenone derivatives is reported. Products of up to 99% ee were formed.
Preparation method of nitrogen-alkyl (deuterated alkyl) aromatic heterocycle and alkyl (deuterated alkyl) aryl ether compound
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Paragraph 0087-0092, (2021/04/03)
The invention provides a method for preparing nitrogen-alkyl(deuterated alkyl)aromatic heterocycle and alkyl(deuterated alkyl)aryl ether compounds. The method adopted in the invention specifically comprises the following steps: firstly, adding an alkoxy base (MOR') or a combination reagent Q (comprising a base M'X, an alcohol C and a molecular sieve E) into a solvent B to be stirred; then, addingan aromatic compound D of nitrogen sulfonyl or oxygen sulfonyl into a mixture; separating and purifying after reaction to obtain nitrogen-alkyl(deuterated alkyl)aromatic heterocycle or alkyl(deuterated alkyl)aryl ether. The method can realize one-step conversion from an electron withdrawing benzenesulfonyl protecting group on a nitrogen or oxygen atom to an electron donating alkyl protecting group, avoids using highly toxic alkyl halide, and has advantages of being efficient, economical, environmentally friendly, mild in condition, good in substrate universality and high in yield; the prepareddeuterated compounds can be widely applied to the fields of pharmaceutical chemistry and organic chemistry synthesis.
Facile C-S Bond Cleavage of Aryl Sulfoxides Promoted by Bronsted Acid
Brutiu, Bogdan R.,Klose, Immo,Maulide, Nuno
supporting information, p. 488 - 490 (2021/03/09)
A method for the Bronsted acid promoted desulfination of aryl sulfoxides is presented. In the presence of a thiol, electron-rich sulfoxides undergo C-S bond cleavage to give the corresponding protodesulfinated arenes and disulfides.