87553-46-6Relevant articles and documents
Total synthesis of (+/-)-syn-copalol.
Toshima, Hiroaki,Oikawa, Hideaki,Yada, Hiroshi,Ono, Hiroshi,Toyomasu, Tomonobu,Sassa, Takeshi
, p. 2504 - 2510 (2002)
The labdane diterpene derivative, syn-copalol [(+)-5] is the alcohol part of syn-copalyl diphosphate [(+)-4]. In this paper, racemic (+/-)-5 was synthesized from a known racemic lactone in 8 steps. The current and our previous syntheses provide all four copalol derivatives [(+)-3, (-)-3 and (+/-)-5] which are required for the biosynthetic study of polycyclic diterpenes.