87701-34-6

Basic information

• Product Name: (2R-trans)-1,4-Dihydro-4-hydroxy-2,4,6-trimethyl-spiro(cyclopropane-1,5-(5H)inden)-3(2H)-one
• CAS NO: 87701-34-6
• Molecular Weight: 218.296
• Mol File: 87701-34-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R-trans)-1,4-Dihydro-4-hydroxy-2,4,6-trimethyl-spiro(cyclopropane-1,5-(5H)inden)-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R-trans)-1,4-Dihydro-4-hydroxy-2,4,6-trimethyl-spiro(cyclopropane-1,5-(5H)inden)-3(2H)-one(87701-34-6)
• EPA Substance Registry System: (2R-trans)-1,4-Dihydro-4-hydroxy-2,4,6-trimethyl-spiro(cyclopropane-1,5-(5H)inden)-3(2H)-one(87701-34-6)

Safety Data

• Hazardous Substances Data: 87701-34-6(Hazardous Substances Data)

Upstream product

• 87625-62-5 ptaquiloside 

Downstream Products

• 60657-37-6 pterosin B 

Relevant articles and documents

An Efficient Method for the Isolation of Toxins from Pteridium aquilinum and Evaluation of Ptaquiloside against Cancer and Non-cancer Cells#

The common fern, bracken (Pteridium aquilinum), is well known for its toxic effects on livestock due principally to the carcinogenic constituent ptaquiloside (1), although other toxins are present including the cyanogenic glycoside, prunasin (2). Here, we report an improved and relatively green process for the isolation of 1 and 2 from fresh bracken fronds and the evaluation of 1 for cytotoxicity against several cancer cell lines. The results indicate that 1 displays selective toxicity against cancer cells relative to noncancer retinal epithelial cells, and the improved method for the isolation of 1 is expected to facilitate further exploration of its pharmacological properties.