87711-71-5

Basic information

• Product Name: 2-Propenoic acid, 3-(4-ethoxyphenyl)-, methyl ester, (E)-
• CAS NO: 87711-71-5
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 87711-71-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-ethoxyphenyl)-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-ethoxyphenyl)-, methyl ester, (E)-(87711-71-5)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-ethoxyphenyl)-, methyl ester, (E)-(87711-71-5)

Safety Data

• Hazardous Substances Data: 87711-71-5(Hazardous Substances Data)

Upstream product

• 61200-99-5 1-(4-Ethoxy-phenyl)-3,3-bis-methylsulfanyl-propenone 
• 67-56-1 methanol 
• 77251-75-3 trans-p-ethoxycinnamoyl chloride 
• 2373-79-7 (E)-4-ethoxycinnamic acid 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 10031-82-0 4-ethoxybenzaldehyde 
• 7400-08-0 p-Coumaric Acid 
• 3943-97-3 methyl 4-hydroxycinnamate 
• 75-03-6 ethyl iodide 
• 87711-80-6 1-(4-Ethoxy-phenyl)-3,3-bis-methylsulfanyl-prop-2-en-1-ol 
• 2373-79-7 4-ethoxycinnamic acid 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 957147-02-3 (E)-3-(4-ethoxyphenyl)prop-2-en-1-ol 
• 1157642-68-6 trans-2-(4-ethoxyphenyl)cyclopropanecarboxylic acid 
• 1226460-07-6 methyl trans-2-(4-ethoxyphenyl)cyclopropanecarboxylate 
• 2373-79-7 (E)-4-ethoxycinnamic acid 
• 1268243-11-3 (E)-3-(4-ethoxystyryl)-[1,2,4]triazolo[3,4-α]phthalazine 
• 1268515-41-8 (2E,N',E)-3-(4-ethoxyphenyl)-N'-[phthalazin-1-(2H)-ylidiene]acrylohydrazide 
• 1268243-05-5 (E)-N'-[3-(4-ethoxyphenyl)propenoyl]isonicotinohydrazide 

Relevant articles and documents

METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS

Described herein are methods of treating breast cancer using arylcyclopropylamine compounds.

METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS

Described herein are methods of treating Parkinson's disease using arylcyclopropylamine compounds.

Design, synthesis, and biological evaluation of new cinnamic derivatives as antituberculosis agents

Tuberculosis, HIV coinfection with TB, emergence of multidrug-resistant TB, and extensively drug-resistant TB are the major causes of death from infectious diseases worldwide. Because no new drug has been introduced in the last several decades, new classes of molecules as anti-TB drugs are urgently needed. Herein, we report the synthesis and structure-activity relationships of a series of thioester, amide, hydrazide, and triazolophthalazine derivatives of 4-alkoxy cinnamic acid. Many compounds exhibited submicromolar minimum inhibitory concentrations against Mycobacterium tuberculosis strain (H37Rv). Interestingly, compound 13e, a 4-isopentenyloxycinnamyl triazolophthalazine derivative, was found to be 100-1800 times more active than isoniazid (INH) when tested for its ability to inhibit the growth of INH-resistant M. tuberculosis strains. The results also revealed that 13e does not interfere with mycolic acid biosynthesis, thereby pointing to a different mode of action and representing an attractive lead compound for the development of new anti-TB agents.