87750-50-3

Basic information

• Product Name: 1-(phenylsulphonyl)-4-(trifluoromethoxy)benzene
• Synonyms: 1-(phenylsulphonyl)-4-(trifluoromethoxy)benzene;Phenyl(4-trifluoromethoxyphenyl) sulfone;Einecs 289-341-6
• CAS NO: 87750-50-3
• Molecular Formula: C₁₃H₉F₃O₃S
• Molecular Weight: 302.2689696
• EINECS: 289-341-6
• Mol File: 87750-50-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 373.9°C at 760 mmHg
• Flash Point: 179.9°C
• Appearance: /
• Density: 1.385g/cm³
• Vapor Pressure: 1.87E-05mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: 1-(phenylsulphonyl)-4-(trifluoromethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(phenylsulphonyl)-4-(trifluoromethoxy)benzene(87750-50-3)
• EPA Substance Registry System: 1-(phenylsulphonyl)-4-(trifluoromethoxy)benzene(87750-50-3)

Safety Data

• Hazardous Substances Data: 87750-50-3(Hazardous Substances Data)

Usage

Structure

A benzene ring with a phenylsulfonyl group and a trifluoromethoxy group attached

Type of compound

Synthetic organic compound

Applications

a. Organic synthesis
b. Medicinal chemistry
c. Building block for the synthesis of pharmaceutical compounds and agrochemicals
d. Development of new drugs and chemotherapeutic agents

Hazardous properties

Potential hazards, should be handled with care

Importance

Widely used in the chemical and pharmaceutical industries due to its versatile structure and potential applications

InChI:InChI=1/C13H9F3O3S/c14-13(15,16)19-10-6-8-12(9-7-10)20(17,18)11-4-2-1-3-5-11/h1-9H

Upstream product

• 456-55-3 1-trifluoromethoxybenzene 
• 98-09-9 benzenesulfonyl chloride 
• 127-63-9 diphenyl sulphone 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Visible-Light-Mediated Late-Stage Sulfonylation of Boronic Acids via N-S Bond Activation of Sulfonamides

A visible-light-mediated late-stage arylation of N-S bonds in sulfonamides has been developed with using readily available imines as sulfonyl radical source. Diverse complex sulfones could be synthesized by prefunctionalizaiton and subsequent N-S bond ary

Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow

The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison t

DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME

The present invention provides a compound having the structure (I), a processing of making the compound; and a process of using the compound as a reagent for the difluoromethoxylation and trifluoromethoxylation of arenes or heteroarenes.