88149-49-9

Basic information

• Product Name: 2,6-Dibromo-4-(trifluoromethoxy)aniline
• Synonyms: 3,5-Dibromo-4-(trifluoromethoxy)aniline;3.5-Dibromo-4-Aminotrifluoromethoxybenzen;3,5-Dibromo-4-Aminotrifluoromethoxy;3,5-dibromo-5-AminoTrifluoromethoxybenzene;4-Amino-3,5-dibromotrifluoromethoxybenzene;2,6-Dibromo-4-(trifluoromethoxy)aniline 97%;2,6-Dibromo-4-(trifluoromethoxy)aniline97%;3,5-DIBROMO-4-AMINOTRIFLUOROMETHOXY BENZENE 99+%
• CAS NO: 88149-49-9
• Molecular Formula: C₇H₄Br₂F₃NO
• Molecular Weight: 334.92
• EINECS: 201-805-1
• Product Categories: amine| alkyl bromide
• Mol File: 88149-49-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 70-74 °C(lit.)
• Boiling Point: 65/0.1mm
• Flash Point: 107.3 °C
• Appearance: /
• Density: 2.036 g/cm³
• Vapor Pressure: 0.0179mmHg at 25°C
• Refractive Index: 1.557
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: -0.38±0.10(Predicted)
• CAS DataBase Reference: 2,6-Dibromo-4-(trifluoromethoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dibromo-4-(trifluoromethoxy)aniline(88149-49-9)
• EPA Substance Registry System: 2,6-Dibromo-4-(trifluoromethoxy)aniline(88149-49-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-60-37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 88149-49-9(Hazardous Substances Data)

Usage

Description

2,6-Dibromo-4-(trifluoromethoxy)aniline is an organic compound characterized by the presence of two bromine atoms at the 2nd and 6th positions, and a trifluoromethoxy group at the 4th position attached to an aniline (amino) group. This unique molecular structure endows it with specific chemical properties that make it suitable for various applications, particularly in the synthesis of complex organic molecules.

Uses

Used in Pharmaceutical Industry:
2,6-Dibromo-4-(trifluoromethoxy)aniline is used as a key intermediate in the synthesis of novel pyridylpyrazole acid derivatives. These derivatives are of significant interest due to their potential applications in the development of new pharmaceutical compounds with improved therapeutic properties.
Used in Agricultural Industry:
2,6-Dibromo-4-(trifluoromethoxy)aniline is used as a chemical building block in the preparation of agricultural insecticides. Its unique structure allows for the creation of new insecticidal agents that can effectively control pests and protect crops, thereby contributing to increased agricultural productivity and food security.

InChI:InChI=1/C7H4Br2F3NO/c8-4-1-3(14-7(10,11)12)2-5(9)6(4)13/h1-2H,13H2

Upstream product

• 461-82-5 4-(trifluoromethoxy)aniline 

Downstream Products

• 1335243-01-0 C₁₅H₁₁F₃N₂O 
• 1335242-71-1 C₂₂H₁₄ClF₃N₂O 
• 175278-17-8 2-bromo-4-trifluoromethoxyaniline 
• 130000-40-7 thifluzamide 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula A, or a pharmaceutically acceptable salt thereof, are featured (Formula A) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

Preparation method of thifluzamide key intermediate, namely 2,6-dibromo-4-(trifluoromethoxy)aniline

The invention discloses a preparation method of a thifluzamide key intermediate, namely 2,6-dibromo-4-(trifluoromethoxy)aniline. The method comprises the following operating steps: (1) adding water into a reaction bottle, dropwise adding concentrated sulf