881678-28-0

Basic information

• Product Name: Carbamic acid, [[1-[(6-chloro-3-pyridinyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl]methyl]methyl-, 1,1-dimethylethyl ester
• CAS NO: 881678-28-0
• Molecular Formula: C22H24ClN3O4S
• Molecular Weight: 461.969
• Mol File: 881678-28-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[1-[(6-chloro-3-pyridinyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl]methyl]methyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[1-[(6-chloro-3-pyridinyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl]methyl]methyl-, 1,1-dimethylethyl ester(881678-28-0)
• EPA Substance Registry System: Carbamic acid, [[1-[(6-chloro-3-pyridinyl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl]methyl]methyl-, 1,1-dimethylethyl ester(881678-28-0)

Safety Data

• Hazardous Substances Data: 881678-28-0(Hazardous Substances Data)

Upstream product

• 6684-39-5 2-chloropyridine-5-sulfonyl chloride 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 881676-94-4 1-(6-chloropyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 161958-61-8 ethyl 5-phenyl-1H-pyrrole-3-carboxylate 
• 158692-57-0 Ethyl 2-chloro-5-phenyl-1H-pyrrole-3-carboxylate 
• 70-11-1 α-bromoacetophenone 
• 22984-74-3 Ethyl 2-cyano-4-oxo-4-phenylbutanoate 
• 56448-22-7 5-phenyl-1H pyrrole-3-carboxaldehyde 
• 881673-96-7 tert-butyl methyl[(5-phenyl-1H-pyrrol-3-yl)methyl]-carbamate 
• 881673-95-6 (5-phenyl-1H-pyrrol-3-yl)methanol 

Downstream Products

• 881678-29-1 tert-butyl methyl({[1-(6-methylpyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl}methyl)carbamate 
• 1374671-92-7 tert-butyl ({[1-(6-cyanopyridin-3-yl)sulfonyl]-5-phenyl-1H-pyrrol-3-yl}methyl)methylcarbamate 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

Acid secretion inhibitor

The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.