88326-51-6

Basic information

• Product Name: cyclopent-3-ene-1,1-dicarboxylic acid
• Synonyms: cyclopent-3-ene-1,1-dicarboxylic acid;3-Cyclopentene-1,1-dicarboxylic acid
• CAS NO: 88326-51-6
• Molecular Formula: C₇H₈O₄
• Molecular Weight: 156.14
• EINECS: -0
• Mol File: 88326-51-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 387.8°Cat760mmHg
• Flash Point: 202.5°C
• Appearance: /
• Density: 1.487g/cm³
• Vapor Pressure: 4.3E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: cyclopent-3-ene-1,1-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cyclopent-3-ene-1,1-dicarboxylic acid(88326-51-6)
• EPA Substance Registry System: cyclopent-3-ene-1,1-dicarboxylic acid(88326-51-6)

Safety Data

• Hazardous Substances Data: 88326-51-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H8O4/c8-5(9)7(6(10)11)3-1-2-4-7/h1-2H,3-4H2,(H,8,9)(H,10,11)

Upstream product

• 1476-11-5 Z-1,4-dichlorobutene 
• 105-53-3 diethyl malonate 
• 7686-78-4 diethyl 2-vinylcyclopropane-1,1-dicarboxylate 
• 108-59-8 malonic acid dimethyl ester 
• 84646-68-4 Dimethyl 3-cyclopentene-1,1-dicarboxylate 
• 21622-00-4 Cyclopent-3-ene-1,1-dicarboxylic acid diethyl ester 
• 4372-31-0 2,2-diallylmalonic acid 

Downstream Products

• 58101-60-3 methyl cyclopent-3-ene-1-carboxylate 
• 1004764-73-1 benzyl (2-{4-[3-(2-methylpyrrolidin-1-yl)propoxy]phenyl}-5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-5-yl)carbamate 
• 1004764-72-0 benzyl {2-[4-(3-chloropropoxy)phenyl]-5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-5-yl}carbamate 
• 89415-65-6 trans-3,4-dibromocyclopentane-1-carboxylic acid 
• 7686-79-5 3-cyclopentenecarboxylic acid phenyl amide 
• 99-14-9 tricarallylic acid 
• 76909-91-6 rel-(1R,5R)-5-(hydroxymethyl)cyclopent-2-en-1-ol 
• 88710-88-7 (3-cyclopentenylmethyl)methylphenylsilane 
• 25125-21-7 4-(hydroxymethyl)cyclopentene 
• 922166-21-0 1-bromo-2-(cyclopent-3-enylmethyl)-3,4-difluorobenzene 
• 7686-77-3 3-cyclopentene-1-carboxylic acid 

Relevant articles and documents

Acetamide scanning around bicyclic thiazoles: SAR at the H3 receptor

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Design and synthesis of spiro-heterocycles by ring-closing metathesis

Synthesis of diverse spiro-heterocyclic compounds via the ring-closing (RCM) metathesis approach is described. Specifically, synthesis of various derivatives of barbituric acid, Meldrum's acid, tetronic acid and thiotetronic acid are described by RCM approach.

Enantioselective synthesis of nicotinic receptor probe 7,8-difluoro-1,2,3, 4,5,6-hexahydro-1,5-methano-3-benzazocine

(Chemical Equation Presented) The development of a concise enantioselective synthesis of nicotinic alkaloid 1 is presented. The route features the synthesis and use of a "stable" aliphatic triflate 21 in an alkylation step to generate Heck precursor 24 and an enantioselective cyclization to establish a compound with the key [3.2.1]-bicyclic core, 29.