885672-69-5 Usage
Description
1-(4-CHLORO-PHENYL)-N3,N3-DIMETHYL-PROPANE-1,3-DIAMINE, with the molecular formula C11H18ClN3, is a chemical compound that belongs to the class of diamines. It features a chlorophenyl group and two N,N-dimethylpropyl substituents, which contribute to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Synthesis:
1-(4-CHLORO-PHENYL)-N3,N3-DIMETHYL-PROPANE-1,3-DIAMINE is used as a building block in the pharmaceutical industry for the synthesis of various medications and biologically active molecules. Its unique structure allows for the creation of new compounds with potential therapeutic properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-CHLORO-PHENYL)-N3,N3-DIMETHYL-PROPANE-1,3-DIAMINE serves as a valuable component in the development of novel drugs. Its versatility and reactivity make it a promising candidate for designing molecules with specific biological activities.
Used in Research and Development:
1-(4-CHLORO-PHENYL)-N3,N3-DIMETHYL-PROPANE-1,3-DIAMINE is also utilized in the research and development of new materials and chemicals. Its properties and reactivity make it a valuable tool for exploring new chemical reactions and creating innovative compounds with potential applications in various industries.
Overall, 1-(4-CHLORO-PHENYL)-N3,N3-DIMETHYL-PROPANE-1,3-DIAMINE is a versatile and valuable chemical compound with diverse applications in the pharmaceutical, medicinal chemistry, and research and development industries. Its unique structure and properties make it a promising building block for the creation of new compounds with potential therapeutic and practical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 885672-69-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,6,7 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 885672-69:
(8*8)+(7*8)+(6*5)+(5*6)+(4*7)+(3*2)+(2*6)+(1*9)=235
235 % 10 = 5
So 885672-69-5 is a valid CAS Registry Number.
885672-69-5Relevant articles and documents
Discovery of 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H- pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an orally bioavailable, potent inhibitor of Akt kinases
Addie, Matt,Ballard, Peter,Buttar, David,Crafter, Claire,Currie, Gordon,Davies, Barry R.,Debreczeni, Judit,Dry, Hannah,Dudley, Philippa,Greenwood, Ryan,Johnson, Paul D.,Kettle, Jason G.,Lane, Clare,Lamont, Gillian,Leach, Andrew,Luke, Richard W. A.,Morris, Jeff,Ogilvie, Donald,Page, Ken,Pass, Martin,Pearson, Stuart,Ruston, Linette
, p. 2059 - 2073 (2013/05/08)
Wide-ranging exploration of analogues of an ATP-competitive pyrrolopyrimidine inhibitor of Akt led to the discovery of clinical candidate AZD5363, which showed increased potency, reduced hERG affinity, and higher selectivity against the closely related AGC kinase ROCK. This compound demonstrated good preclinical drug metabolism and pharmacokinetics (DMPK) properties and, after oral dosing, showed pharmacodynamic knockdown of phosphorylation of Akt and downstream biomarkers in vivo, and inhibition of tumor growth in a breast cancer xenograft model.
UII-MODULATING COMPOUNDS AND THEIR USE
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Page/Page column 37, (2010/11/25)
Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.
