88980-54-5 Usage
Description
(2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one is a steroidal compound with a unique hexahydroxycholesterol structure. It is a derivative of cholesterol, characterized by the presence of hydroxyl groups at the 2, 3, 5, 14, 20, and 22 positions. (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one also features a double bond at the 7th position and a ketone group at the 6th position. This chemical possesses potential biological activity and may be involved in various physiological processes. Its structure and properties make it a significant molecule of interest in the fields of biochemistry and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one is used as a research compound for investigating its potential biological activity and role in physiological processes. Its unique structure and properties make it a valuable molecule for exploring new therapeutic applications and understanding its impact on human health.
Used in Biochemical Studies:
In the field of biochemistry, (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one is utilized as a model compound to study the interactions between cholesterol and its derivatives. This can provide insights into the mechanisms of cholesterol metabolism and the development of new drugs targeting cholesterol-related diseases.
Used in Drug Development:
(2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one is employed as a lead compound in drug development, with the aim of designing and synthesizing new pharmaceutical agents that can modulate cholesterol levels and treat related disorders. Its unique structure offers opportunities for the creation of innovative therapeutics with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 88980-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,8 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 88980-54:
(7*8)+(6*8)+(5*9)+(4*8)+(3*0)+(2*5)+(1*4)=195
195 % 10 = 5
So 88980-54-5 is a valid CAS Registry Number.
88980-54-5Relevant articles and documents
ECDYSTEROID METABOLISM IN A CRAB: CARCINUS MAENAS L.
Lachaise, Fabienne,Lafont, Rene
, p. 243 - 260 (2007/10/02)
Ponasterone A (25-deoxy-20-hydroxyecdysone) and 20-hydroxyecdysone were the major ecdysteroids detected in crab hemolymph, although some ecdysone was also present.The metabolism of ponasterone A was examined in intermolt and premolt crabs either by injecting the radiolabeled hormone or by incubating tissues in its presence.Metabolites were extracted from the surrounding seawater and from tissues and separated by high-performance liquid chromatography.Ponasterone A metabolism proceeds through (1) C-25 and C-26 hydroxylation, followed by formation of inactivation products via oxidation of the terminal alcoholic group to a carboxylic residue, (2) conjugation, (3) binding to very polar compounds and (4) side-chain scission.The conversion of ponasterone A into 20-hydroxyecdysone, inokosterone (25-deoxy-20,26-dihydroxyecdysone), 20,26-dihydroxyecdysone and ecdysonoic acids, as well as the formation of conjugates and of very polar compounds, occurs in various tissues.These metabolites were excreted by both intermolt and premolt crabs.
