9008-42-8

Basic information

• Product Name: SILVER PROTEIN
• Synonyms: ALBUMOSE SILVER;PROTARGIN;PROTARGOL;PROTARGOL S;PROTARGOL S(TM);SILVER, COLLOIDAL;SILVER, COLLOIDAL, MILD;SILVER, COLLOIDAL, STRONG
• CAS NO: 9008-42-8
• Molecular Weight: 0
• EINECS: 685-470-0
• Mol File: 9008-42-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Water Solubility: Soluble in water. Slightly soluble in methanol, diethyl ether.
• Sensitive: Hygroscopic
• CAS DataBase Reference: SILVER PROTEIN(CAS DataBase Reference)
• NIST Chemistry Reference: SILVER PROTEIN(9008-42-8)
• EPA Substance Registry System: SILVER PROTEIN(9008-42-8)

Safety Data

• Safety Statements: 24/25
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: UK9510000
• F: 8-10-21
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 9008-42-8(Hazardous Substances Data)

Usage

Description

Silver protein, also known as silver-stained protein, is a unique compound formed by the interaction of silver ions with proteins. It possesses distinctive staining properties and is known for its affinity towards certain biological molecules. The formation of silver protein involves the binding of silver ions to the amino, carboxyl, and thiol groups present in proteins, resulting in a stable complex that exhibits enhanced staining characteristics.
Source:
Silver protein is typically synthesized through the chemical reduction of silver ions in the presence of proteins, which can be derived from various biological sources.
Production Methods:
The production of silver protein involves a process where silver ions are reduced and simultaneously bind to the functional groups of proteins. This can be achieved through various chemical reduction methods, such as using sodium borohydride or other reducing agents, which facilitate the formation of silver nanoparticles that are stabilized by the protein matrix.

Uses

Used in Electron Microscopy:
Silver protein is used as a positive stain for carbohydrates in electron microscopy, particularly when combined with periodic acid and thiocarbohydrazide or thiosemicarbohydrazide. This application takes advantage of the selective binding of silver ions to specific carbohydrate structures, allowing for enhanced visualization and analysis of glycogen and other carbohydrate-rich regions within the sample.
Used in Light Microscopy:
In light microscopy, silver protein is employed as a staining agent for nerve tissue. The unique staining properties of silver protein enable the clear visualization of neuronal structures, which is crucial for the study of the nervous system and the diagnosis of various neurological disorders.
Used in Histological Stain for Microscopic Analysis:
Silver protein is also utilized in histological staining for microscopic analysis. Its ability to selectively bind and stain specific cellular components makes it a valuable tool in the field of histology, where it can be used to identify and differentiate various types of cells and tissues, as well as to detect specific cellular structures and abnormalities.