906532-18-1Relevant articles and documents
Rearrangement of ethers: A new route to tolterodine
Arava, Veera Reddy,Bandatmakuru, Sreenivasula Reddy,Malreddy, Sashibhushan,Golla, Narayanaswamy
, p. 1565 - 1571 (2011/06/27)
The rearrangement of benzyl phenolic ether in the presence of an acid or AlCl3 is utilized to produce biphenyl methane compounds in very good yields. The synthesis of muscarine receptor antagonist tolterodine is described.
Process for the preparation of tolterodine
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Page/Page column 4-5, (2008/06/13)
A novel process for the preparation of tolterodine, i.e. (R)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamine, in the racemic form, as well as intermediates useful for its preparation.