908072-60-6Relevant articles and documents
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum
Chiang, Annette N.,Valderramos, Juan-Carlos,Balachandran, Raghavan,Chovatiya, Raj J.,Mead, Brian P.,Schneider, Corinne,Bell, Samantha L.,Klein, Michael G.,Huryn, Donna M.,Chen, Xiaojiang S.,Day, Billy W.,Fidock, David A.,Wipf, Peter,Brodsky, Jeffrey L.
experimental part, p. 1527 - 1533 (2009/09/27)
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle. In any organism, Hsp70 chaperones are typicall