914076-03-2

Basic information

• Product Name: 6,8-Dioxa-3-azabicyclo[3.2.1]octane-7-carboxamide, N-([1,1'-biphenyl]-4-ylmethyl)-3-(phenylmethyl)-, (1S,5S,7R)-
• CAS NO: 914076-03-2
• Molecular Formula: C26H26N2O3
• Molecular Weight: 414.504
• Mol File: 914076-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,8-Dioxa-3-azabicyclo[3.2.1]octane-7-carboxamide, N-([1,1'-biphenyl]-4-ylmethyl)-3-(phenylmethyl)-, (1S,5S,7R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-Dioxa-3-azabicyclo[3.2.1]octane-7-carboxamide, N-([1,1'-biphenyl]-4-ylmethyl)-3-(phenylmethyl)-, (1S,5S,7R)-(914076-03-2)
• EPA Substance Registry System: 6,8-Dioxa-3-azabicyclo[3.2.1]octane-7-carboxamide, N-([1,1'-biphenyl]-4-ylmethyl)-3-(phenylmethyl)-, (1S,5S,7R)-(914076-03-2)

Safety Data

• Hazardous Substances Data: 914076-03-2(Hazardous Substances Data)

Upstream product

• 712-76-5 N-(4-phenyl)benzylamine 
• 250137-88-3 methyl (1S,5S,7R)-3-benzyl-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-exo-carboxylate 

Downstream Products

• 914076-04-3 (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-7-carboxylic acid ((biphenyl-4-yl)methyl)amide 
• 914076-05-4 (1S,5S,7R)-3-aza-6,8-dioxabicyclo[3.2.1]octane-3,7-dicarboxylic acid 3-(benzyloxy)amide 7-((biphenyl-4-yl)methyl)amide 

Relevant articles and documents

Synthesis of bicyclic molecular scaffolds (BTAa): An investigation towards new selective MMP-12 inhibitors

Starting from 3-aza-6,8-dioxa-bicyclo[3.2.1]octane scaffold (BTAa) a virtual library of molecules was generated and screened in silico against the crystal structure of the Human Macrophage Metalloelastase (MMP-12). The molecules obtaining high score were