91449-79-5

Basic information

• Product Name: HEPARIN
• Synonyms: DALTEPARIN;ENOXAPARIN;TINZAPARIN
• CAS NO: 91449-79-5
• Molecular Formula: C26H42N2O37S5
• Molecular Weight: 1134.92788
• EINECS: 232-681-7
• Mol File: 91449-79-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 2.13g/cm³
• Refractive Index: 1.711
• CAS DataBase Reference: HEPARIN(CAS DataBase Reference)
• NIST Chemistry Reference: HEPARIN(91449-79-5)
• EPA Substance Registry System: HEPARIN(91449-79-5)

Safety Data

• Hazardous Substances Data: 91449-79-5(Hazardous Substances Data)

Usage

Description

HEPARIN is a sulfated glycosaminoglycan that is highly effective as an anticoagulant. It is a natural polysaccharide composed of alternating D-glucosamine and uronic acid residues, with molecular weights ranging from 3,000 to 30,000 Daltons. HEPARIN is known for its ability to prevent blood clots by inactivating thrombin and factor Xa, making it a crucial component in the management of various thrombotic disorders.
Used in Pharmaceutical Industry:
HEPARIN is used as an anticoagulant for the treatment of venous thromboembolism, a condition characterized by the formation of blood clots in the deep veins of the legs or lungs. It helps to prevent the clots from growing and reduces the risk of complications such as pulmonary embolism.
HEPARIN is also used as a prophylactic agent to prevent coagulation in the extracorporeal circulation during hemodialysis. This application is crucial for patients with chronic kidney disease who require regular dialysis treatments, as it helps to maintain the patency of the dialysis circuit and minimize the risk of clot formation.
In addition to its primary use as an anticoagulant, HEPARIN has been found to possess other therapeutic properties, such as anti-inflammatory and antithrombotic effects, which have led to its exploration in various other medical applications. However, it is important to note that the provided materials only specifically mention its use in the treatment of venous thromboembolism and prevention of coagulation during hemodialysis.

InChI:InChI=1/C26H41NO34S4/c1-4(28)27-7-9(30)8(29)6(2-52-63(43,44)45)53-24(7)56-15-10(31)11(32)25(58-19(15)21(36)37)55-13-5(3-62(40,41)42)14(60-64(46,47)48)26(59-22(13)38)57-16-12(33)17(61-65(49,50)51)23(39)54-18(16)20(34)35/h5-19,22-26,29-33,38-39H,2-3H2,1H3,(H,27,28)(H,34,35)(H,36,37)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)/t5-,6+,7+,8+,9+,10+,11+,12-,13-,14+,15-,16-,17+,18+,19-,22-,23?,24+,25+,26-/m0/s1