914772-92-2Relevant articles and documents
Rational design, synthesis, biological evaluation, homology and docking studies of coumarin derivatives as α1-adrenoceptor antagonists
Zhou, Xiang,Chen, Ya-Dong,Wang, Tao,Wang, Xiao-Bing,Kong, Ling-Yi
, p. 1052 - 1064 (2012/01/06)
According to a three-point pharmacophore for some uro-selective α1-adrenoceptor (AR) antagonists, a novel class of coumarin (=2H-1-benzopyran-2-one) derivatives have been successfully designed and synthesized with high efficacies for α1/s