91912-29-7Relevant articles and documents
Synthesis of Ketene Aminals with an Imidazoline Ring by Condensation of 4,5-Dihydro-2-(methylthio)-1H-imidazoles with Active Methylene Compounds and Some Addition and Cyclocondensation Reactions
Huang, Zhi-tang,Tzai, Lu-hang
, p. 2208 - 2219 (2007/10/02)
The 4,5-dihydro-2-(methylthio)-1H-imidazoles 1a, b react with active methylene compounds 2a - f to afford the corresponding substituted methyleneimidazolines 3a - f and 4c - f by elimination of methanethiol.The reaction of compounds 2g - j, which contain a more active carbonyl group, with 1a gives 3g - i by elimination of a methylthio group as well as an acyl group, too. 3a, g - i react with esters of α,β-unsaturated acids to afford the corresponding imidazopyridines 5, 6, and 7 in an addition and cyclocondensation reaction sequence, but with diethyl azodicarboxylate only to give the addition product 8.
