92007-54-0Relevant articles and documents
Inhibitors of acyl-CoA:Cholesterol O-acyltransferase. 17. Structure-activity relationships of several series of compounds derived from N-chlorosulfonyl isocyanate
Picard, Joseph A.,O'Brien, Patrick M.,Sliskovic, Drago R.,Anderson, Maureen K.,Bousley, Richard F.,Hamelehle, Katherine L.,Krause, Brian R.,Stanfield, Richard L.
, p. 1243 - 1252 (2007/10/03)
Several series of acyl-CoA:cholesterol O-acyltransferase inhibitors were prepared by the stepwise addition of nitrogen, oxygen, and sulfur nucleophiles to N-chlorosulfonyl isocyanate. The (aminosulfonyl)ureas 3-44 were the most potent inhibitors in vitro,
Aminosulfonyl carbamates
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, (2008/06/13)
A compound of the following general formula which is useful in treating hypocholesterolemia and atherosclerosis: STR1 wherein X is oxygen or sulfur; R is hydrogen, alkyl having from 1 to 8 carbon atoms, or benzyl; R1 is phenyl, substituted phen