92114-64-2

Basic information

• Product Name: 2-nitro-4-(phenylthio)aniline
• Synonyms: 2-nitro-4-(phenylthio)aniline
• CAS NO: 92114-64-2
• Molecular Weight: 246.29
• Mol File: 92114-64-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-nitro-4-(phenylthio)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitro-4-(phenylthio)aniline(92114-64-2)
• EPA Substance Registry System: 2-nitro-4-(phenylthio)aniline(92114-64-2)

Safety Data

• Hazardous Substances Data: 92114-64-2(Hazardous Substances Data)

Upstream product

• 54394-50-2 2-Nitro-4-phenylsulfinyl-anilin 
• 26877-95-2 4-Chlor-3-nitrobenzoldiazoniumchlorid 
• 14204-24-1 N-(phenylthio)succinimide 
• 88-74-4 2-nitro-aniline 
• 62-53-3 aniline 
• 54029-45-7 2-nitro-4-thiocyanoaniline 
• 108-86-1 bromobenzene 
• 5228-61-5 5-bromo-2-nitroaniline 
• 930-69-8 sodium thiophenolate 
• 92114-63-1 2-Nitro-4-phenylsulfinyl-N-phenylsulfonyl-anilin 
• 92114-62-0 4-Phenylsulfinyl-N-phenylsulfonyl-anilin 
• 92114-61-9 4-Phenylthio-N-phenylsulfonyl-anilin 
• 92114-67-5 2-Nitro-4-phenylsulfinyl-chlorbenzol 
• 92114-68-6 2-Nitro-4-phenylthio-chlorbenzol 

Downstream Products

• 43156-48-5 1,2-diamino-4-phenylthiobenzene 

Relevant articles and documents

Preparation method of 4-thiophenyl-o-phenylenediamine

The invention provides a preparation method of 4-thiophenyl-o-phenylenediamine, wherein the preparation method comprises the steps: by taking 2-nitro-4-thiocyano aniline and aniline as initial raw materials, firstly, reacting 2-nitro-4-thiocyano aniline with sodium sulfide to obtain 3-nitro-4-amino thiophenol sodium, and reacting aniline with sodium nitrite under an acidic condition to generate benzene diazonium chloride; and then condensing the benzene diazonium chloride and the 3-nitro-4-amino thiophenol sodium to obtain 2-nitro-4-thiophenyl aniline, and then carrying out a Raney nickel hydrogenation reduction reaction to obtain the 4-thiophenyl-o-phenylenediamine. The method has the characteristics of high economic benefit, low three-waste amount, low cost and the like, the total yield can reach 64.58%, and the method belongs to the technical field of organic chemical industry.

Preparation method of fenbendazole intermediate 2-nitro-4-phenylthioaniline

The invention relates to the technical field of veterinary drugs, and in particular, relates to a preparation method of fenbendazole intermediate 2-nitro-4-phenylthioaniline. The preparation method comprises the following steps: by taking o-nitroaniline and ammonium thiocyanate as raw materials and an organic solvent as a solvent of a reaction system, uniformly stirring and mixing, introducing chlorine, and filtering after the reaction of the raw materials is finished, so as to obtain 4-thiocyano-2-nitroaniline; taking 4-thiocyano-2-nitroaniline, adding sodium hydroxide and a reaction solvent,stirring and mixing, and filtering after the reaction is finished to obtain a sodium 4-amino-3-nitrothiophenol solution; carrying out a reaction on the sodium 4-amino-3-nitrothiophenol solution withbromobenzene under an alkaline condition, and after the reaction is finished, extracting to obtain the 2-nitro-4-phenylthioaniline. The preparation method is simple in process, the production cost isreduced, the production potential safety hazard can be reduced, the product yield is relatively high, and the environmental pollution is reduced.

Arylthiolation of arylamine derivatives with (arylthio)-pyrrolidine-2,5-diones

A simple and efficient method for arylthiolation of arylamines has been developed. The protocol uses (arylthio)pyrrolidine-2,5-diones as the arylthiolating reagents, acetonitrile as the solvent, and no catalyst and additive are required, which avoids contamination from the transition metal catalysts in the target products. Therefore, the present method should provide a convenient, efficient and practical strategy for the synthesis of other aryl sulfides.