92248-73-2

Basic information

• Product Name: 4-(naphthalen-2-ylsulfonyl)morpholine
• CAS NO: 92248-73-2
• Molecular Weight: 277.344
• Mol File: 92248-73-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(naphthalen-2-ylsulfonyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(naphthalen-2-ylsulfonyl)morpholine(92248-73-2)
• EPA Substance Registry System: 4-(naphthalen-2-ylsulfonyl)morpholine(92248-73-2)

Safety Data

• Hazardous Substances Data: 92248-73-2(Hazardous Substances Data)

Upstream product

• 1828-66-6 morpholine-4-sulfonyl chloride 
• 32316-92-0 naphthalene-2-boronic acid 

Relevant articles and documents

S(vi) in three-component sulfonamide synthesis: Use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki-Miyaura coupling

Sulfuric chloride is used as the source of the -SO2- group in a palladium-catalyzed three-component synthesis of sulfonamides. Suzuki-Miyaura coupling between the in situ generated sulfamoyl chlorides and boronic acids gives rise to diverse sulfonamides in moderate to high yields with excellent reaction selectivity. Although this transformation is not workable for primary amines or anilines, the results show high functional group tolerance. With the solving of the desulfonylation problem and utilization of cheap and easily accessible sulfuric chloride as the source of sulfur dioxide, redox-neutral three-component synthesis of sulfonamides is first achieved. This journal is