92254-02-9 Usage
Description
6-Methyl-2-phenylbenzoic acid, also known as tolfenamic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. It works by inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation.
Used in Pharmaceutical Industry:
6-Methyl-2-phenylbenzoic acid is used as an anti-inflammatory agent for its ability to reduce pain, fever, and inflammation. It is commonly used to treat conditions such as rheumatoid arthritis, osteoarthritis, and menstrual pain.
Used in Pain Management:
6-Methyl-2-phenylbenzoic acid is used as a pain reliever for its effectiveness in alleviating acute pain. It is often prescribed as a short-term treatment for conditions that cause severe discomfort.
Used in Topical Medications:
6-Methyl-2-phenylbenzoic acid is used as an active ingredient in topical formulations for its ability to provide localized relief from pain and inflammation.
Used with Caution in Individuals with Gastrointestinal Issues:
6-Methyl-2-phenylbenzoic acid should be used with caution in individuals with a history of gastrointestinal ulcers or bleeding, as it may exacerbate these conditions.
Used with Caution in Individuals with Liver and Kidney Issues:
6-Methyl-2-phenylbenzoic acid may have adverse effects on the liver and kidneys, and should be used with caution in individuals with pre-existing liver or kidney conditions.
Used with Consultation of Healthcare Professional:
It is important to consult a healthcare professional before using 6-methyl-2-phenylbenzoic acid, as it may interact with other medications and have potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 92254-02-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,2,5 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92254-02:
(7*9)+(6*2)+(5*2)+(4*5)+(3*4)+(2*0)+(1*2)=119
119 % 10 = 9
So 92254-02-9 is a valid CAS Registry Number.
92254-02-9Relevant articles and documents
Palladium-Catalyzed Direct C(sp2)-H ortho-Arylation of Anilides Using 2-Aminophenylpyrazole as the Directing Group
Shen, Yuning,Cindy Lee, Wan-Chen,Gutierrez, David A.,Li, Jie Jack
, p. 11620 - 11625 (2017/11/10)
Palladium-catalyzed ortho-arylation of anilides was achieved using 2-aminophenyl-1H-pyrazole (2-APP) as a new directing group. Using Pd(OAc)2 as the catalyst and AgO as the promoter, mono- and diarylation of anilides were realized in up to 89% isolated yield. Further manipulation of the arylation product may be accomplished by a 2-step sequence involving an acidic hydrolysis of the methylated amide. More interestingly, in the presence of K2CO3, tandem C-C/C-N cyclization products were obtained for a couple of substrates.
