923-01-3 Usage
Synthesis Reference(s)
Tetrahedron, 22, p. 2303, 1966 DOI: 10.1016/S0040-4020(01)82149-9
Metabolism
In the living plant, 3-cyanoalanine is mainly bound as its gama-glutamyl derivative. The enzyme, beta-cyanoalanine synthase, catalysing the reaction between cysteine and cyanide has been isolated from seedlings of the blue lupin (Lupinus angustifolius, Leguminosae).
3-Cyanoalanine is a neurotoxin, causing convulsions and muscular rigidity in rats and chicks. In rats, the compound also causes cystathioninuria, the lethai dose being 20mg/100g body weight. This metabolic defect can be prevented by injection of pyridoxal phosphate. Thus, beta-cyanoalanine interferes with pyridoxal metabolism and inhibits the enzyme gama-cystathionase.
In non-accumulating plants, 3-cyanoalanine is enzymatically hydrolysed to the protein amino acid, asparagine, by 3-cyanoalanine hydrolase. Thus, this nonprotein amino acid could be a ubiquitous constituent of plants, but may only accumulate in those species whieh do not contain 3-cyanoalanine hydrolase.
Check Digit Verification of cas no
The CAS Registry Mumber 923-01-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,2 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 923-01:
(5*9)+(4*2)+(3*3)+(2*0)+(1*1)=63
63 % 10 = 3
So 923-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)
