924-99-2

Basic information

• Product Name: Ethyl 3-(N,N-dimethylamino)acrylate
• Synonyms: DMAE;ETHYL 3-(DIMETHYLAMINO)ACRYLATE;ETHYL 3,3-DIMETHYLAMINOACRYLATE;3-(DIMETHYLAMINO)ACRYLIC ACID ETHYL ESTER;3-DAASE;RARECHEM AL BI 0671;Ethyl 3-(N,N-dimethylamino)acrylate, 99+%;ethyl 3-(dimethylamino)propenoate
• CAS NO: 924-99-2
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18
• EINECS: 402-650-4
• Product Categories: Acids and Derivatives;Amines and Anilines;Small molecule;API intermediates
• Mol File: 924-99-2.mol
• Article Data: 11

Chemical Properties

• Melting Point: 17-18 °C
• Boiling Point: 118-121 °C (7.501 mmHg)
• Flash Point: 105 °C
• Appearance: Clear yellow to light orange/Liquid
• Density: 1
• Vapor Pressure: 0.683mmHg at 25°C
• Refractive Index: 1.5105-1.5125
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.67±0.70(Predicted)
• Water Solubility: 90 g/L (25 ºC)
• CAS DataBase Reference: Ethyl 3-(N,N-dimethylamino)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(N,N-dimethylamino)acrylate(924-99-2)
• EPA Substance Registry System: Ethyl 3-(N,N-dimethylamino)acrylate(924-99-2)

Safety Data

• Hazard Codes: Xi
• Statements: 43-36/37/38
• Safety Statements: 37-24-36/37-26
• Hazardous Substances Data: 924-99-2(Hazardous Substances Data)

Usage

Description

Ethyl 3-(N,N-dimethylamino)acrylate is an organic compound that serves as a crucial raw material and intermediate in various chemical processes. It is characterized by its unique chemical structure, which includes an ethyl group, a dimethylamino group, and an acrylate moiety. This versatile molecule is known for its reactivity and ability to form a wide range of derivatives, making it a valuable component in numerous applications across different industries.

Uses

Used in Organic Synthesis:
Ethyl 3-(N,N-dimethylamino)acrylate is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its reactivity allows for the formation of a diverse array of products, making it an essential component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, Ethyl 3-(N,N-dimethylamino)acrylate is utilized as a building block for the development of new drugs. Its unique chemical properties enable the creation of innovative pharmaceutical agents with potential therapeutic applications.
Used in Agrochemicals:
Ethyl 3-(N,N-dimethylamino)acrylate is employed as a vital component in the formulation of agrochemicals, such as pesticides and herbicides. Its incorporation into these products contributes to their effectiveness in controlling pests and promoting crop health.
Used in Dye Industry:
In the dyestuff field, Ethyl 3-(N,N-dimethylamino)acrylate is used as a precursor for the synthesis of various dyes and pigments. Its ability to form a wide range of derivatives makes it a valuable asset in the production of colorants for textiles, plastics, and other materials.

InChI:InChI=1/C7H13NO2/c1-4-10-7(9)5-6-8(2)3/h5-6H,4H2,1-3H3/b6-5+

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 927-80-0 1-ethoxyacetylene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 64-18-6 formic acid 
• 141-78-6 ethyl acetate 
• 124-40-3 dimethyl amine 
• 201230-82-2 carbon monoxide 
• 20120-21-2 ethyl 3-(N,N-dimethylamino)propionate 
• 127-19-5 N,N-dimethyl acetamide 
• 506-59-2 N,N-dimethylammonium chloride 
• 20353-93-9 Gold's reagent 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 74119-34-9 3-Dimethylamino-2-(formylaminomethyl)acrylsaeure-ethylester 

Downstream Products

• 148926-94-7 ethyl ester of 3-dimethylamino-2-(5-nitro-2,4-dichlorobenzoyl)acrylic acid 
• 1208000-20-7 ethyl (2Z)-2-(2,6-difluorobenzoyl)-3-(dimethylamino)acrylate 
• 103877-51-6 ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 103877-38-9 ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-methylbenzoyl)acrylate 
• 25770-53-0 N-tosyl-N',N'-dimethylformamidine 
• 59291-72-4 ethyl 3-phenyl-isoxazole-4-carboxylate 

Relevant articles and documents

Preparation method of ethyl 3-(N,N-dimethylamino)acrylate

The invention relates to a preparation method of ethyl 3-(N,N-dimethylamino)acrylate, which comprises the following steps: carrying out heating reaction on formic acid, ethyl acetate and dimethylamineto obtain ethyl 3-(N,N-dimethylamino)acrylate and water. The preparation method of the ethyl 3-(N,N-dimethylamino)acrylate is short in reaction route, high in yield and purity and low in safety risk.

Ethyl N,N-dimethylaminoacrylate synthesis method

The invention relates to the technical field of synthesis of fine chemical intermediates, particularly to an ethyl N,N-dimethylaminoacrylate synthesis method, which comprises that ethyl acetate, carbon monoxide and dimethylamine are used as starting raw materials, and are subjected to a reaction under the action of a solid alkali catalyst to form the target product ethyl N,N-dimethylaminoacrylate,wherein the solid alkali catalyst is preferably a supported solid alkali catalyst. According to the present invention, the problems that the raw material source is difficult, the price is expensive,the process condition is harsh, the three-waste amount is high, the yield is low, the cost is high, the method is not suitable for industrial production and the like in the prior art are solved; and the synthesis method of the present invention has characteristics of convenient raw material source, low cost, environmentally-friendly reaction condition, substantially-reduced side-product, high total yield, high raw material utilization rate, low production cost and high product purity, and is suitable for large-scale industrial continuous production.

Gold nanoparticles on OMS-2 for heterogeneously catalyzed aerobic oxidative α,β-dehydrogenation of β-heteroatom-substituted ketones

In the presence of Au nanoparticles supported on manganese oxide OMS-2 (Au/OMS-2), various kinds of β-heteroatom-substituted α,β-unsaturated ketones (heteroatom = N, O, S) can be synthesized through α,β-dehydrogenation of the corresponding saturated ketones using O2 (in air) as the oxidant. The catalysis of Au/OMS-2 is truly heterogeneous, and the catalyst can be reused.