92493-11-3

Basic information

• Product Name: 1-(4-PHENOXYBUTYL)PIPERAZINE
• Synonyms: 1-(4-Phenoxybut-1-yl)piperazine97%;1-(4-PHENOXYBUTYL)PIPERAZINE;[4-(Piperazin-1-yl)butoxy]benzene;1-(4-Phenoxybut-1-yl)piperazine 97%;1-(4-Phenoxybut-1-yl)piperazine
• CAS NO: 92493-11-3
• Molecular Formula: C₁₄H₂₂N₂O
• Molecular Weight: 234.34
• Product Categories: piperazines
• Mol File: 92493-11-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 121-122°C
• Boiling Point: 363.4°Cat760mmHg
• Flash Point: 173.6°C
• Appearance: /
• Density: 1.007g/cm³
• Vapor Pressure: 1.8E-05mmHg at 25°C
• Refractive Index: 1.515
• PKA: 9.24±0.10(Predicted)
• CAS DataBase Reference: 1-(4-PHENOXYBUTYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-PHENOXYBUTYL)PIPERAZINE(92493-11-3)
• EPA Substance Registry System: 1-(4-PHENOXYBUTYL)PIPERAZINE(92493-11-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 92493-11-3(Hazardous Substances Data)

Usage

General Description

1-(4-Phenoxybutyl)piperazine is a chemical compound that belongs to the class of piperazine derivatives. It is a white to off-white crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. 1-(4-PHENOXYBUTYL)PIPERAZINE has been identified as a potential endocrine disruptor and has also been studied for its potential use as an antifungal agent. It is important to handle 1-(4-Phenoxybutyl)piperazine with caution and in compliance with safety regulations, as it may pose health and environmental risks if not properly managed.

InChI:InChI=1/C14H22N2O/c1-2-6-14(7-3-1)17-13-5-4-10-16-11-8-15-9-12-16/h1-3,6-7,15H,4-5,8-13H2

Upstream product

• 2651-46-9 (4-chlorobutoxy)benzene 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 110-85-0 piperazine 
• 1200-03-9 4-bromophenyl butyl ether 
• 7755-92-2 piperazine-1-carbaldehyde 
• 531522-73-3 [4-(4-phenoxy-butyl)-piperazin-1-yl]-phenyl-methanone 

Downstream Products

• 1383806-30-1 C₁₇H₂₉N₃O 
• 1383806-59-4 C₁₇H₂₅N₃O 

Relevant articles and documents

1-Phenoxyalkyl-4-[(N,N-disubstitutedamino)alkyl]piperazine derivatives as non-imidazole histamine H3-antagonists

In this study, a series of 1-phenoxyalkyl-4-[(N,N-disubstitutedamino)alkyl] piperazine derivatives has been prepared and in vitro tested as H 3-receptor antagonists (electrically evoked contraction of the guinea pig jejunum). All compounds inve

Unique spirocyclopiperazinium salt I: Synthesis and structure-activity relationship of spirocyclopiperazinium salts as analgesics

Based on the structure of compound 3, two series of spirocyclopiperazinium derivatives 7a-n and 10a-h were synthesized and evaluated for their in vivo analgesic and sedative activities. Compounds 7f and 10c were discovered to exhibit excellent analgesic activity. Structure-activity relationships revealed that anion of the quaternary salt affected the analgesic and sedative activity significantly; the allyl group is a most effective group among the compounds 7a-n; the electron-released substitute on the aromatic ring is favorable to increase the analgesic activity.

2-(substituted-1-piperazinyl)[1,2,4]triazolo[1,5-a]pyrimidines

This disclosure describes novel 2-(4-substituted-1-piperazinyl)[1,2,4]triazolo[1,5-a]pyrimidines useful as hypotensive agents.