92496-58-7

Basic information

• Product Name: 3-ethoxy-6H-benzo[c]chromen-6-one
• Synonyms: 3-ethoxy-6H-benzo[c]chromen-6-one
• CAS NO: 92496-58-7
• Molecular Formula: C15H12O3
• Molecular Weight: 240.25398
• Mol File: 92496-58-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-ethoxy-6H-benzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethoxy-6H-benzo[c]chromen-6-one(92496-58-7)
• EPA Substance Registry System: 3-ethoxy-6H-benzo[c]chromen-6-one(92496-58-7)

Safety Data

• Hazardous Substances Data: 92496-58-7(Hazardous Substances Data)

Upstream product

• 669713-70-6 3'-ethoxy-[1,1'-biphenyl]-2-carboxylic acid 
• 74-96-4 ethyl bromide 
• 1139-83-9 urolithin B 
• 88-65-3 2-bromobenzoic-acid 
• 108-46-3 recorcinol 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel 6h-benzo[c]chromen-6-one derivatives as potential phosphodiesterase ii inhibitors

Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. As part of this research, a series of alkoxylated 6H-benzo[c]chromen-6-one derivatives were designed and synthesized. Furthermore, their biological activities were evaluated as potential PDE2 inhibitors, and the alkoxylated 6H-benzo[c]chromen-6-one derivative 1f was found to have the optimal inhibitory potential (IC50: 3.67 ± 0.47 μM). It also exhibited comparable activity in comparison to that of BAY 60-7550 in vitro cell level studies.