925693-54-5

Basic information

• Product Name: Ethanone, 2-chloro-2-fluoro-1-(4-methoxyphenyl)-
• CAS NO: 925693-54-5
• Molecular Formula: C9H8ClFO2
• Molecular Weight: 202.613
• Mol File: 925693-54-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-2-fluoro-1-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-2-fluoro-1-(4-methoxyphenyl)-(925693-54-5)
• EPA Substance Registry System: Ethanone, 2-chloro-2-fluoro-1-(4-methoxyphenyl)-(925693-54-5)

Safety Data

• Hazardous Substances Data: 925693-54-5(Hazardous Substances Data)

Upstream product

• 16629-92-8 2,2-dichloro-2-fluoro-1-(4-methoxyphenyl)ethanol 
• 401-56-9 ethyl chlorofluoroacetate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 16629-88-2 2,2-dichloro-2-fluoro-1-(4-methoxyphenyl) ethanone 

Downstream Products

• 947504-05-4 (E)-N-(2-chloro-2-fluoro-1-(4-methoxyphenyl)ethylidene)isopropylamine 
• 947504-15-6 N-(2-chloro-2-fluoro-1-(4-methoxyphenyl)ethyl)-N-isopropylamine 

Relevant articles and documents

New synthetic routes towards various α-fluorinated aryl ketones and their enantioselective reductions using baker's yeast

Highly electrophilic dichlorofluoromethyl aryl ketones were obtained by oxidation of dichlorofluoromethyl aryl alcohols. Subsequent dechlorination of these ketones using sodium formaldehyde sulfoxylate (Rongalite) and reductive dehalogenating system SnCl2/Al led to various fluoromethyl aryl ketones and chlorofluoromethyl aryl ketones, respectively. Asymmetric reductions of these fluorinated ketones using the inexpensive baker's yeast produced the corresponding fluoromethyl aryl alcohols with different enantioselectivities.