931-35-1Relevant articles and documents
Environment-friendly 2-ethyl-4-methylimidazole synthesis method
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Paragraph 0006; 0007; 0008, (2020/03/09)
The invention discloses an environment-friendly synthesis method of 2-ethyl-4-methylimidazole, and belongs to the technical field of organic synthesis. The method comprises: generating aminopropyl propionamide at a temperature of 80 DEG C from low-toxicity methyl propionate and 1,2-diaminopropane according to a proper reaction ratio; carrying out cyclization with water on the aminopropyl propionamide and an aromatic hydrocarbon in the presence of a catalyst to generate 2-ethyl-4-methylimidazoline; and dehydrogenating the 2-ethyl-4-methylimidazoline at a temperature of 120-40 DEG C in the presence of a pd/c catalyst to prepare the 2-ethyl-4-methylimidazole. According to the invention, the 2-ethyl-4-methylimidazole is prepared by using the method, so that the use of high-toxicity propionitrile, high-pollution aldehyde and ammonia and high-risk Raney nickel catalysts capable of burning in the presence of air are avoided, no waste ammonia is generated in the production process, and the method belongs to an environment-friendly method for preparing the 2-ethyl-4-methylimidazole.
Preparation method of 2-ethyl-4-methylimidazole
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Paragraph 0019; 0030, (2016/10/10)
The invention discloses a preparation method of 2-ethyl-4-methylimidazole. The preparation method comprises steps as follows: diamine and propionitrile have a cyclization reaction sequentially at the temperature of 80-110 DEG C and 120-140 DEG C under the catalysis of a catalyst; a product after the cyclization reaction has a dehydrogenation reaction through raney nickel at the temperature of 170-200 DEG C, and 2-ethyl-4-methylimidazole is obtained. The preparation method has the advantages that 2-ethyl-4-methylimidazole is prepared with a substep method, the process cost is reduced, the reaction process is optimized, the operation is simple and convenient, the pollution is reduced, and the reaction yield is high.