936247-35-7

Basic information

• Product Name: 5-chloro-2-nitro-pyridine-3-ol
• Synonyms: 5-chloro-2-nitro-pyridine-3-ol;5-Chloro-2-nitropyridin-3-ol
• CAS NO: 936247-35-7
• Molecular Formula: C₅H₃ClN₂O₃
• Molecular Weight: 174.54192
• EINECS: -0
• Mol File: 936247-35-7.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-chloro-2-nitro-pyridine-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-nitro-pyridine-3-ol(936247-35-7)
• EPA Substance Registry System: 5-chloro-2-nitro-pyridine-3-ol(936247-35-7)

Safety Data

• Hazardous Substances Data: 936247-35-7(Hazardous Substances Data)

Usage

Description

5-chloro-2-nitro-pyridine-3-ol is a chemical compound with the molecular formula C5H3ClN2O3. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-chloro-2-nitro-pyridine-3-ol is known for its ability to undergo various chemical reactions, including nitration, reduction, and substitution reactions. It also serves as a building block in the production of pyridine derivatives and other functionalized heterocycles. Due to its potential hazards, such as skin and eye irritation, and possible harmful effects if ingested or inhaled, it is important to handle this chemical with caution.

Uses

Used in Pharmaceutical Industry:
5-chloro-2-nitro-pyridine-3-ol is used as a key intermediate in the synthesis of various pharmaceuticals. Its versatility in undergoing chemical reactions allows for the creation of a wide range of drug molecules, contributing to the development of new medications and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 5-chloro-2-nitro-pyridine-3-ol is utilized as an intermediate for the production of pesticides and other agrochemicals. Its reactivity and ability to form various derivatives make it a valuable component in the synthesis of compounds that can protect crops and enhance agricultural productivity.
Used in the Synthesis of Pyridine Derivatives:
5-chloro-2-nitro-pyridine-3-ol is used as a building block in the synthesis of pyridine derivatives. These derivatives are important in various chemical and pharmaceutical applications, including the development of new drugs and the creation of novel chemical compounds with specific properties.
Used in the Production of Functionalized Heterocycles:
5-chloro-2-nitro-pyridine-3-ol is also used in the production of functionalized heterocycles, which are important in organic chemistry and have applications in various fields, such as materials science, medicinal chemistry, and the development of new chemical technologies.

Upstream product

• 74115-12-1 5-chloropyridin-3-ol 

Downstream Products

• 936247-05-1 3-benzyloxy-5-chloro-2-nitro-pyridine 
• 1609164-93-3 6-chloro-8-[(2,6-difluorobenzyl)oxy]-N-[(2R)-1-hydroxyhexan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide 
• 1609341-91-4 N-[(3S)-3-aminobutan-2-yl]-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide 
• 1609341-92-5 N-[(3S)-3-aminobutan-2-yl]-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide 
• 1609348-02-8 tert-butyl {1-[({6-chloro-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridin-3-yl}carbonyl)amino]-3-methylbutan-2-yl}carbamate 
• 1609348-03-9 C₂₆H₃₁ClF₂N₄O₄ 
• 1609164-89-7 6-chloro-8-[(2,6-difluorobenzyl)oxy]-N-[(2R)-1,5-dihydroxypentan-2-yl]-2-methylimidazo[1,2-a]-pyridine-3-carboxamide 
• 1609082-28-1 5-chloro-3-[(2,6-difluorobenzyl)oxy]-2-nitropyridine 
• 1609341-14-1 N-(3-Amino-3-methylbutyl)-6-chloro-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]-pyridine-3-carboxamide 
• 1609340-83-1 N-(2-amino-2-methylpropyl)-6-chloro-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide 

Relevant articles and documents

ENANTIOMERS OF THE N-(2-AMINO-5-FLUORO-2-METHYLPENTYL)-8-[(2,6-DIFLUOROBENZYL)OXY]-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDE, AS WELL AS OF THE DI- AND TRIFLUORO DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES

The present application relates to novel 6-hydrogen-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.

IMIDAZO[1,2-A]PYRIDINES AS SOLUBLE GUANYLATE CYCLASE STIMULATORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.

CYANO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.