939400-11-0Relevant articles and documents
Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid
Bieliauskas, Anton V.,Weerasinghe, Sujith V.W.,Pflum, Mary Kay H.
, p. 2216 - 2219 (2007/10/03)
Inhibitors of histone deacetylase (HDAC) proteins such as suberoylanilide hydroxamic acid (SAHA) have emerged as effective therapeutic anti-cancer agents. To better understand the structural requirements of HDAC inhibitors, a small molecule library with a