93987-17-8Relevant articles and documents
Synthesis, 3D pharmacophore, QSAR and docking studies of novel quinazoline derivatives with nitric oxide release moiety as preferential COX-2 inhibitors
Farag, Doaa Boshra,Farag, Nahla A.,Esmat, Ahmed,Abuelezz, Sally A.,Abdel-Salam Ibrahim, Eman,Abou El Ella, Dalal A.
, p. 283 - 299 (2015)
Four novel series of 1-substituted-3-(2-methyl-4-oxo-4H-quinazolin-3-yl) urea and/or thiourea IIIa-c, 4-substituted-N-(2-methyl-4-oxo-4H-quinazolin-3-yl) benzene sulfonamide VIa-c and their NO-hybrid molecules as nitrate esters Va-c and VIIIa-c have been
Newer Quinazolinone Derivatives as Anthelmintic Agents
Gupta, D. P.,Ahmad, S.,Kumar, Ashok,Shanker, K.
, p. 1060 - 1062 (2007/10/02)
Five types of quinazolinone derivatives have been synthesized. 3-Amino-2-methyl-4(3H)-quinazolinones (I) on treatment with chloroacetyl chloride give the 3-chloroacetamido derivatives (II) which react with secondary and primary amines to afford the corresponding 3-substituted acetamido derivatives (III and IV).The 3-amino-quinazolinones (I) also react with aryl and alkyl halides to afford the corresponding 3-aryl/alkyl-amino derivatives (V-VII).These compounds (III-VII) have been tested for their acetylcholinesterase inhibitory activity and anthelmintic activity against H. nana.