94243-46-6

Basic information

• Product Name: 1H,3H-8-acetyl-4,5-dihydronaphto<1,2-c:4,3-b'>difuran-1-one
• CAS NO: 94243-46-6
• Molecular Weight: 268.269
• Mol File: 94243-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H,3H-8-acetyl-4,5-dihydronaphto<1,2-c:4,3-b'>difuran-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,3H-8-acetyl-4,5-dihydronaphto<1,2-c:4,3-b'>difuran-1-one(94243-46-6)
• EPA Substance Registry System: 1H,3H-8-acetyl-4,5-dihydronaphto<1,2-c:4,3-b'>difuran-1-one(94243-46-6)

Safety Data

• Hazardous Substances Data: 94243-46-6(Hazardous Substances Data)

Upstream product

• 5061-21-2 α-bromo-γ-butyrolactone 
• 16475-90-4 estere metilico dell'acido 5-acetilsalicilico 
• 80901-29-7 methyl 5-acetyl-2-<(tetrahydro-2-oxo-3-furanyl)oxyl>benzoate 

Relevant articles and documents

Spirocyclopropane compounds. V. One-step synthesis of 5-acetyl-spiro[benzofuran-2(3H),1'-cyclopropan]-3-one

5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one (3a, AG-629), previously found to be the most potent antiulcer compound in a series of spirocyclopropanes, was obtained by one step synthesis starting from methyl 5-acetyl-2-[(tetrahydro-2-oxo-3-furanyl)oxy]benzoate (1a). In this reaction, 5,10'-(diacetyl-5',6'-dihydrospiro[benzofuran-2(3H),4'(3'H)-[2H]oxocino[3, 2-b]-benzofuran]-3-one (5a), which has a new ring system, and 1H,3H-8-acetyl-4,5-dihydro-naphtho[1,2-c:4,3-b']difuran-1-one (6) were isolated as by-products. A possible reaction mechanism is presented.