94275-62-4

Basic information

• Product Name: Benzene, 1-(chloromethyl)-2-(2-phenylethyl)-
• CAS NO: 94275-62-4
• Molecular Formula: C15H15Cl
• Molecular Weight: 230.737
• Mol File: 94275-62-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(chloromethyl)-2-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(chloromethyl)-2-(2-phenylethyl)-(94275-62-4)
• EPA Substance Registry System: Benzene, 1-(chloromethyl)-2-(2-phenylethyl)-(94275-62-4)

Safety Data

• Hazardous Substances Data: 94275-62-4(Hazardous Substances Data)

Upstream product

• 835-78-9 [2-(2-phenylethyl)phenyl]methanol 
• 194605-53-3 methyl 2-(2-phenylethyl)benzoate 

Relevant articles and documents

Modulation of pharmacological profile of diphenylethane (lefetamine- type) derivatives

With the aim to split the pharmacological properties of lefetamine (CAS 14148-99-3), some structural modifications of this compound have been studied. The basic group of lefetamine has been shifted from the alkyl chain to the vicinal phenyl ring and the N-substitution has been changed. The dimethylaminomethyl derivatives and chiefly the o-morpholinometyhl exhibited a strong anti-visceral chemical antinociception activity stripped of thermal antinociception properties and physical dependence liability. Furthermore through the introduction of a diethylaminomethyl group in the lefetamine structure some derivatives were selected exhibiting besided a significant increase in the anti-visceral chemical antinociception activity, remarkable local anesthetic properties.