943323-35-1

Basic information

• Product Name: (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl 2-aMino-3-phenylpropylcarbaMate;N-(2-amino-3-phenylpropyl)Carbamic acid 1,1-dimethylethyl ester
• CAS NO: 943323-35-1
• Molecular Formula: C₁₄H₂₂N₂O₂
• Molecular Weight: 250.34
• Mol File: 943323-35-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(943323-35-1)
• EPA Substance Registry System: (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER(943323-35-1)

Safety Data

• Hazardous Substances Data: 943323-35-1(Hazardous Substances Data)

Usage

General Description

The chemical (2-amino-3-phenyl-propyl)-carbamic acid tert-butyl ester is an organic compound with the chemical formula C13H20N2O2. It is a carbamate compound used in the pharmaceutical industry as a reagent in the synthesis of various drugs and pharmaceutical compounds. The tert-butyl ester group is commonly used to protect the amino group in organic synthesis. (2-AMINO-3-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER is also used as an intermediate in the production of agricultural chemicals and in the manufacture of dyes and pigments. Additionally, it has potential applications in the field of material science and as a building block for the synthesis of complex organic molecules.

Upstream product

• 50411-26-2 3-phenyl-2-hydroxypropylamine 
• 4436-24-2 1,2-epoxy-3-phenylpropane 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 162541-45-9 (RS)-2-<(tert-Butoxycarbonyl)amino>-1-benzylethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 22820-51-5 1-amino-3-phenylpropan-2-ol hydrochloride 
• 1044851-42-4 1,1-dimethylethyl [2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropyl]carbamate 

Downstream Products

• 1047644-81-4 1,1-dimethylethyl (2-{[(4,5-dibromo-2-furanyl)carbonyl]amino}-3-phenylpropyl)carbamate 
• 1047645-24-8 1,1-dimethylethyl (2-{[(5-bromo-1-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-phenylpropyl)carbamate 
• 1047645-23-7 1,1-dimethylethyl (2-{[(4,5-dibromo-1-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-phenylpropyl)carbamate 
• 1047644-99-4 1,1-dimethylethyl [2-({[4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1047645-14-6 1,1-dimethylethyl [2-({[4-(1-methyl-4-phenyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1047645-29-3 1,1-dimethylethyl (2-{[(4-bromo-1-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-phenylpropyl)carbamate 
• 1047645-62-4 1,1-dimethylethyl [2-({[3-(methyloxy)-4-(1-methyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1044851-84-4 1,1-dimethylethyl [2-({[5-bromo-2-(3-furanyl)-3-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 943325-63-1 C₂₀H₂₅BrN₂O₄S 
• 943324-12-7 1,1-dimethylethyl {2-[({3,4-dibromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate 
• 943324-16-1 1,1-dimethylethyl [2-({[4-bromo-3-(4-methylphenyl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1246617-10-6 C₂₄H₂₂N₂O₅ 
• 1246617-11-7 C₂₆H₂₆N₂O₅ 
• 1246617-12-8 C₂₅H₂₄N₂O₅ 

Relevant articles and documents

A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides

A novel strategy for the synthesis of stereochemically defined 3,4,5-trisubstituted 2-pyrrolidones was developed. The suggested approach involves reductive domino-type recyclization of 3-aminomethyl-substituted isoxazolines as a key stage. The latter are prepared via α-C-H functionalization of readily available isoxazoline-N-oxides.

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R2, R3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.

INHIBITORS OF AKT ACTIVITY

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