944060-66-6Relevant articles and documents
Synthesis and biological studies of new quinazolines with ether functions in position 2
Brahmaiah, Dabbugoddu,Bhavani, Anagani Kanaka Durga,Aparna, Pasula,Kumar, Nangunoori Sampath,Solhi, Hélène,Le Guevel, Rémy,Baratte, Blandine,Ruchaud, Sandrine,Bach, Stéphane,Mosset, Paul,Grée, René
, p. 96 - 107 (2019/05/15)
A series of new quinazolines linked to triazoles through an ether chain in position 2 has been designed and synthetized through a flexible route. Cytotoxicity assays on selected cancer cell lines and inhibition studies toward a panel of representative mam
NEUROLOGICALLY-ACTIVE COMPOUNDS
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Page 40; 53, (2010/02/06)
The present invention relates to neurologically-active compounds, being heterocyclic compounds having two fused 6-membered rings with a nitrogen atom at position 1 and a hydroxy or mercapto group at position 8 with at least one ring being aromatic. Also disclosed are processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological conditions, more specifically neurodegenerative conditions such as Alzheimer's disease.