944393-27-5Relevant articles and documents
NOVEL PSYMBERIN DERIVATIVES, COMPOSITIONS, AND THEIR USE AS ANTINEOPLASTIC AGENTS
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, (2010/01/30)
The present invention provides compounds according to Formula (I): or pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, and isomers thereof, wherein: ring A, n, q, R1, R2, R3, R4, R5, R6, each R7, each R7A, and R8 are each selected independently of each other and as defined herein. The invention also provides pharmaceutical compositions comprising such compounds (optionally in combination with one or more additional active ingredients), and methods for their use in treating or preventing a wide range of cancers.
The total synthesis of psymberin
Huang, Xianhai,Shao, Ning,Palani, Anandan,Aslanian, Robert,Buevich, Alexei
, p. 2597 - 2600 (2008/02/08)
The total synthesis of a new member of the pederin family of natural products, psymberln 1, was accomplished. Using a recently reported novel and efficient Phl(OAc)2 mediated oxldatlve entry to 2-(N-acylaminal)- substituted tetrahydropyrans as