945531-29-3

Basic information

• Product Name: 5-bromo-2-(p-tolyl)benzo[d]oxazole
• Synonyms: 5-bromo-2-(p-tolyl)benzo[d]oxazole
• CAS NO: 945531-29-3
• Molecular Weight: 288.143
• Mol File: 945531-29-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-(p-tolyl)benzo[d]oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-(p-tolyl)benzo[d]oxazole(945531-29-3)
• EPA Substance Registry System: 5-bromo-2-(p-tolyl)benzo[d]oxazole(945531-29-3)

Safety Data

• Hazardous Substances Data: 945531-29-3(Hazardous Substances Data)

Upstream product

• 132244-31-6 5-bromo-1,3-benzoxazole 
• 36719-51-4 3,3-diethyl-1-(4-methylphenyl)-1-triazene 
• 615-58-7 2,4-dibromophenol 
• 6326-27-8 p-methylbenzamidine hydrochloride 
• 65440-82-6 O-(4-bromophenyl)hydroxylamine 
• 328081-49-8 (p-bromo-N-phenoxy)phthalimide 
• 5467-74-3 4-Bromophenylboronic acid 
• 1310486-76-0 C₁₄H₁₂BrNO 

Relevant articles and documents

Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes

A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.

Copper-mediated synthesis of substituted 2-aryl-N-benzylbenzimidazoles and 2-arylbenzoxazoles via C-H functionalization/C-N/C-O bond formation

An efficient method for the transformation of N-benzyl bisarylhydrazones and bisaryloxime ethers to functionalized 2-aryl-N-benzylbenzimidazoles and 2-arylbenzoxazoles is described. The protocol involves a copper(II)-mediated cascade C-H functionalization/C-N/C-O bond formation under neutral conditions. Substrates having either electron-donating or -withdrawing substituents undergo the cyclization to afford the target heterocycles at moderate temperature.