95-27-2 Usage
Description
Dimazole, also known as Asterol, is a pharmaceutical compound primarily used in veterinary medicine. It is a derivative of imidazole and possesses antifungal and antibacterial properties. Its chemical structure allows it to inhibit the synthesis of ergosterol, an essential component of fungal cell membranes, thereby exerting its antifungal effect.
Uses
Used in Veterinary Medicine:
Dimazole is used as an antifungal and antibacterial agent for the treatment of various fungal and bacterial infections in animals. It is particularly effective against dermatophytes, yeasts, and certain bacteria, making it a valuable asset in managing skin, ear, and respiratory infections in pets and livestock.
Used in Antifungal Treatments:
Dimazole is used as an antifungal agent for the treatment of fungal infections in animals, such as ringworm and other dermatophyte infections. Its ability to inhibit ergosterol synthesis makes it an effective treatment option for these conditions.
Used in Antibacterial Treatments:
Dimazole is also used as an antibacterial agent for the treatment of bacterial infections in animals. Its broad-spectrum activity against certain bacteria makes it a useful tool in managing infections caused by these pathogens.
Brand names and formulations:
Dimazole is available under various brand names, such as Asterol (as dihydrochloride), Atelora, Aterola, Kesten, and Mycotol. It is typically formulated as a veterinary medication for the treatment of fungal and bacterial infections in animals.
Therapeutic Function
Antifungal
World Health Organization (WHO)
Dimazole, an antifungal agent, was introduced in 1951 for the
treatment of tinea infections. Although the major manufacturer subsequently
discontinued marketing preparations in the United States, the US Food and Drug
Administration formally withdrew marketing approval for such preparations in 1977
on the grounds of their association with severe neurotoxic reactions, their
potential for misuse and the availability of safer alternative products. Topical
preparations of dimazole remain available in some 40 countries.
Check Digit Verification of cas no
The CAS Registry Mumber 95-27-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 95-27:
(4*9)+(3*5)+(2*2)+(1*7)=62
62 % 10 = 2
So 95-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H23N3OS/c1-5-18(6-2)9-10-19-12-7-8-13-14(11-12)20-15(16-13)17(3)4/h7-8,11H,5-6,9-10H2,1-4H3
