95-50-1

Basic information

• Product Name: o-Dichlorobenzene
• Synonyms: Benzene,o-dichloro- (8CI);Cloroben;Dilatin DB;Dowtherm E;NSC60644;o-Dichlorobenzene
• CAS NO: 95-50-1
• Molecular Formula: C₆H₄Cl₂
• Molecular Weight: 147.00196
• EINECS: 202-425-9
• Mol File: 95-50-1.mol
• Article Data: 116

Chemical Properties

• Melting Point: -15℃
• Boiling Point: 180.479 °C at 760 mmHg
• Flash Point: 65.556 °C
• Appearance: colourless liquid
• Density: 1.297 g/cm³
• Vapor Density: 5.1 (vs air)
• Vapor Pressure: 1.21mmHg at 25°C
• Refractive Index: 1.548
• Water Solubility: 0.13 g/L (20℃)
• CAS DataBase Reference: o-Dichlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: o-Dichlorobenzene(95-50-1)
• EPA Substance Registry System: o-Dichlorobenzene(95-50-1)

Safety Data

• Hazard Codes: Xn:Harmful;;
• Statements: R22:; R36/37/38:; R50/53:
• Safety Statements: S23:; S60:; S61:
• RIDADR: 1591
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 95-50-1(Hazardous Substances Data)

Usage

General Description

Ortho-Dichlorobenzene (o-Dichlorobenzene) is a volatile, colorless, non-flammable, liquid organic compound that belongs to the family of aromatic hydrocarbon compounds, with the chemical formula C6H4Cl2. Known for its strong, distinctive smell, it is commonly used as an industrial solvent, degreasant, chemical intermediate, and is found in some insecticides. Exposure to o-Dichlorobenzene can occur through inhalation, skin contact, or ingestion, and may cause harmful health effects such as irritation of the eyes, skin, and throat, dizziness, and liver damage in higher concentrations. It is considered to be potentially carcinogenic by several health organizations.

Upstream product

• 577-19-5 2-nitrophenyl bromide 
• 88-73-3 2-Chloronitrobenzene 
• 541-73-1 1,3-Dichlorobenzene 
• 120-82-1 1,2,4-Trichlorobenzene 
• 108-90-7 chlorobenzene 
• 56-23-5 tetrachloromethane 
• 58468-76-1 (2-chloro-phenyl)-cis-diazenecarbonitrile 
• 7647-01-0 hydrogenchloride 
• 7446-70-0 aluminium trichloride 
• 7553-56-2 iodine 
• 7782-50-5 chlorine 
• 71-43-2 benzene 
• 7705-08-0 iron(III) chloride 
• 7697-37-2 nitric acid 

Downstream Products

• 52192-59-3 (3,4-dichloro-phenyl)-[2]furyl ketone 
• 55441-63-9 3,9-dimethyluric acid 
• 6284-79-3 3,4-dichlorobenzophenone 
• 1146-38-9 (4-chloro-phenyl)-(3,4-dichloro-phenyl)-sulfone 
• 2642-63-9 3',4'-dichloroacetophenone 
• 18173-97-2 dichloro-(2-chloro-phenyl)-methyl-silane 
• 108-90-7 chlorobenzene 
• 253185-02-3 ortho-diethylbenzene 
• 6623-59-2 1,2-dichloro-4-ethylbenzene 
• 102-47-6 3,4-Dichlorophenylmethyl chloride 
• 105410-12-6 N,N'-bis-(8-benzoylamino-9,10-dioxo-9,10-dihydro-[1]anthryl)-oxalamide 
• 87-85-4 Hexamethylbenzene 
• 5324-68-5 1,3,5-trichloro-2,4,6-trimethylbenzene 
• 91-15-6 phthalonitrile 

Relevant articles and documents

Facile Synthesis of a Fully Fused, Three-Dimensional ?-Conjugated Archimedean Cage with Magnetically Shielded Cavity

The synthesis of molecular cages consisting of fully fused, ?-conjugated rings is rare due to synthetic challenges including preorganization, large strain, and poor solubility. Herein, we report such an example in which a tris-2-aminobenzophenone precursor undergoes acid-mediated self-condensation to form a truncated tetrahedron, one of the 13 Archimedean solids. Formation of eight-membered [1,5]diazocine rings provides preorganization and releases the strain while still maintains weak ?-conjugation of the backbone. Thorough characterizations were performed by X-ray, NMR, and UV-vis analysis, assisted by theoretical calculations. The cage exhibits a rigid backbone structure with a well-defined cavity that confines a magnetically shielded environment. The solvent molecule, o-dichlorobenzene, is precisely encapsulated in the cavity at a 1:1 ratio with multiple ?···?, C-H···?, and halogen···πinteractions with the cage skeleton, implying its template effect for the cage closing reaction. Our synthetic strategy opens the opportunity to access more complex, fully fused, three-dimensional ?-conjugated cages.

NUCLEANT ENHANCING NUCLEATION OF A PROTEIN CRYSTAL AND PROTEIN CRYSTALLIZATION METHOD WITH THE SAME

A balanced-lattice-ledge nucleant having ledge inducing local densification of proteins and a balanced-lattice inducing self-organized crystal packing. Using this balanced-lattice-ledge nucleant enhances nucleation of protein crystals.