950577-02-3 Usage
Description
6-Bromo-7-fluoroquinazolin-4-ol is a chemical compound with the molecular formula C9H5BrF2N2O. It is a quinazoline derivative, characterized by a quinazoline ring with bromine and fluorine substituents. 6-BROMO-7-FLUOROQUINAZOLIN-4-OL may possess potential pharmaceutical applications due to its unique structural and chemical properties, which allow it to interact with biological systems and serve as a building block for the synthesis of more complex molecules. The presence of bromine and fluorine atoms in its structure may further contribute to its pharmacological properties and reactivity in chemical reactions.
Uses
Used in Pharmaceutical Industry:
6-Bromo-7-fluoroquinazolin-4-ol is used as a potential pharmaceutical candidate for the development of new drugs. Its unique structure and chemical properties make it a promising compound for the treatment of various diseases and conditions. The bromine and fluorine substituents in its structure may enhance its pharmacological properties, such as its ability to target specific biological pathways or receptors.
Used in Chemical Synthesis:
6-Bromo-7-fluoroquinazolin-4-ol is used as a building block in the synthesis of more complex molecules. Its quinazoline ring and halogen substituents can be further modified or functionalized to create a variety of new compounds with different properties and applications. This makes it a valuable intermediate in the development of novel pharmaceuticals, agrochemicals, or other specialty chemicals.
Further research and testing would be required to fully understand the potential uses and effects of 6-bromo-7-fluoroquinazolin-4-ol, as well as to optimize its synthesis and application in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 950577-02-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,0,5,7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 950577-02:
(8*9)+(7*5)+(6*0)+(5*5)+(4*7)+(3*7)+(2*0)+(1*2)=183
183 % 10 = 3
So 950577-02-3 is a valid CAS Registry Number.
950577-02-3Relevant articles and documents
An alternative synthesis of the non-small cell lung carcinoma drug afatinib
Kovacevic, Tatjana,Mesic, Milan,Avdagic, Amir,Zegarac, Miroslav
supporting information, p. 4180 - 4182 (2018/10/24)
Afatinib (BIBW2992) is the anticancer drug developed by Boehringer Ingelheim. This work is reporting the synthesis of the afatinib using a new route by Ullmann-Goldberg reaction from corresponding 4-anilinoquinazoline iodide as the last step in the synthesis. This route was not described previously and it could be used for synthesis of afatinib analogues.
HETEROCYCLIC CARBOXYLIC ACID AMIDES AS PDK1 INIHIBITORS
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Page/Page column 81, (2011/11/06)
The present invention encompasses compounds of general formula (1) wherein the groups R1 to R4, Qa, Qb, QH, L and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain such compounds and their use as medicaments.
