95184-61-5

Basic information

• Product Name: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone
• Synonyms: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone;(5-bromothiophen-2-yl)(4-methoxyphenyl)methanone
• CAS NO: 95184-61-5
• Molecular Formula: C₁₂H₉BrO₂S
• Molecular Weight: 297.16766
• Mol File: 95184-61-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 408.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.506±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(95184-61-5)
• EPA Substance Registry System: (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone(95184-61-5)

Safety Data

• Hazardous Substances Data: 95184-61-5(Hazardous Substances Data)

Usage

Description

(5-bromo-2-thienyl)(4-methoxyphenyl)Methanone, an organic compound with the molecular formula C11H9BrO2S, belongs to the class of phenyl ketones. It is characterized by its unique structure and functional groups, which make it a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
(5-bromo-2-thienyl)(4-methoxyphenyl)Methanone is used as a building block for the synthesis of various pharmaceuticals. Its unique structure and functional groups contribute to the development of new drugs with therapeutic properties, making it an important intermediate in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical industry, (5-bromo-2-thienyl)(4-methoxyphenyl)Methanone serves as a key component in the creation of various agrochemicals, playing a crucial role in the development of products for agricultural applications.
Used in Organic Synthesis:
(5-bromo-2-thienyl)(4-methoxyphenyl)Methanone is also utilized in the field of organic synthesis due to its varied reactivity and properties, allowing for the creation of a wide range of chemical products.
Used in Material Science:
(5-bromo-2-thienyl)(4-methoxyphenyl)Methanone may have potential applications in material science, where its unique properties can be harnessed to develop new materials with specific characteristics and functionalities.

Upstream product

• 151073-94-8 5-bromo-2-thienylzinc bromide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 4160-63-8 2-(4-methoxybenzoyl)thiophene 
• 1003-09-4 2-bromothiophene 

Downstream Products

• 651365-34-3 (5-bromo-[2]thienyl)-(4-hydroxy-phenyl)-ketone 
• 1617505-98-2 (5-(4-(hydroxymethyl)phenyl)thiophen-2-yl)(3-hydroxyphenyl)-methanone 
• 1617506-03-2 (4-hydroxyphenyl)-(5-(3-hydroxyphenyl)sulfanylthiophen-2-yl)methanone 
• 1617506-04-3 (5-(3-hydroxybenzenesulfonyl)-thiophen-2-yl)(4-hydroxyphenyl)methanone 
• 1617506-17-8 (5-(4-(hydroxymethyl)phenyl)thiophen-2-yl)-(3-methoxyphenyl)methanone 
• 1617506-24-7 (4-methoxyphenyl)-(5-(3-methoxyphenyl)sulfanylthiophen-2-yl)methanone 

Relevant articles and documents

Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker

Estradiol is the most potent estrogen in humans. It is known to be involved in the development and proliferation of estrogen dependent diseases such as breast cancer and endometriosis. The last step of its biosynthesis is catalyzed by 17β-hydroxysteroid d

Polymer-supported syntheses of thiophene-containing compounds using a new type of traceless linker

A new type of traceless linker is described for use in polymer-supported (PS) syntheses of thiophene-containing compounds. It is based on the cleavage of PS aryl 2-thienyl ketones by a mixture of potassium t-butoxide and water (typical mol ratio 10:3) in an ethereal solvent. Cleavage occurs to give the soluble thiophene-containing product. The method is used to prepare a range of eight thiophene-containing compounds including a terthiophene and a dialkylquaterthiophene. PS unsymmetrical diaryl ketones incorporating, for example, ortho-methoxyphenyl or pyrrole moieties could also serve as traceless linkers.