95971-74-7

Basic information

• Product Name: Acetamide, N-(1-phenylbutyl)-
• CAS NO: 95971-74-7
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 95971-74-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(1-phenylbutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(1-phenylbutyl)-(95971-74-7)
• EPA Substance Registry System: Acetamide, N-(1-phenylbutyl)-(95971-74-7)

Safety Data

• Hazardous Substances Data: 95971-74-7(Hazardous Substances Data)

Upstream product

• 2941-19-7 1-phenyl-butylamine 
• 104-51-8 1-butylbenzene 
• 75-05-8 acetonitrile 
• 177750-36-6 (E)-N-(1-phenylbut-1-en-1-yl)acetamide 
• 614-14-2 1-Phenyl-1-butanol 
• 108-24-7 acetic anhydride 
• 872220-83-2 2-(4-methoxybenzylsulfinyl)-N-methylbenzamide 
• 872220-84-3 N-methyl-2-(4-(trifluoromethyl)benzylsulfinyl)benzamide 
• 2527-66-4 2-methyl-1,2-benzisothiazole-3(2H)-one 
• 54705-19-0 2-(benzylthio)-N-methylbenzamide 
• 101093-83-8 2-(4-methoxy-benzylsulfanyl)-benzoic acid 
• 20054-45-9 N-methyl-2-sulfanylbenzamide 
• 1050884-48-4 2-(4-trifluoromethyl-benzylsulfanyl)-benzoic acid 
• 147-93-3 Thiosalicylic acid 

Relevant articles and documents

Method for synthesizing amide compound

The invention discloses a method for the synthesizing a compound as shown in a formula I which is described in the specification. The method comprises a step of subjecting a compound II, a compound III and a compound IV to reaction in the presence of a catalyst to form the compound as shown in the formula I, wherein the compound II is one selected from compounds as shown in a formula II; the compound III is at least one selected from compounds as shown in a formula III-1 and a formula III-2; the compound IV is one selected from compounds as shown in a formula IV; R3 and R4 are independently selected from a group consisting of an alkyl group, a substituted alkyl group, a heteroaryl group and a substituted heteroaryl group.

An umpolung sulfoxide reagent for use as a functionalized benzyl carbanion equivalent

N-Methyl ortho-carbamoylaryl benzyl sulfoxides can be used as synthetic equivalents for α-hydroxy, α-chloro, and α-acetammido benzyl carbanions by means of a two-step sequence involving highly diastereoselective α-C-alkylation with alkyl halides followed by displacement of the sulfinyl residue (which can be recovered and recycled) by a hydroxyl, a chlorine or an acetamido, respectively, under non-oxidative Pummerer conditions. The scope and limits of the method, including a stereoselective version of the reaction, as well as the mechanism of the process are discussed in detail.

The ritter reaction under truly catalytic bronsted acid conditions

Simple organic acids like 2,4-dinitrobenzenesulfonic acid (DNBSA) catalyze the Ritter reaction of secondary benzylic alcohols giving rise to the corresponding N-benzylacetamides in usually high yields. Reactions can be conducted without exclusion of oxygen and without the need of dry solvents. With tertiary α,α-dimethylbenzylic alcohols a different pathway involving a formal dimerization reaction takes place under the acid-catalytic conditions used. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.