96-01-5

Basic information

• Product Name: Sebacile
• Synonyms: Sebacile;NISTC96015;1,2-Cyclodecanedione
• CAS NO: 96-01-5
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 0
• Mol File: 96-01-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 40-41°
• Boiling Point: bp18 120-125°; bp10 104-105°
• Flash Point: 106.2°C
• Appearance: /
• Density: 0.9812 (rough estimate)
• Vapor Pressure: 0.00572mmHg at 25°C
• Refractive Index: 1.4578 (estimate)
• CAS DataBase Reference: Sebacile(CAS DataBase Reference)
• NIST Chemistry Reference: Sebacile(96-01-5)
• EPA Substance Registry System: Sebacile(96-01-5)

Safety Data

• Hazardous Substances Data: 96-01-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 16, p. 869, 1973 DOI: 10.1021/jm00266a001Organic Syntheses, Coll. Vol. 4, p. 838, 1963

InChI:InChI=1/C10H16O2/c11-9-7-5-3-1-2-4-6-8-10(9)12/h1-8H2

Upstream product

• 100703-65-9 2-(methylthio)cyclodecanone 
• 100703-66-0 2-(methylthio)cycloundecanone 
• 106-79-6 dimethyl sebacate 
• 110-40-7 diethyl sebacate 
• 878-13-7 cycloundecanone 
• 1502-06-3 cyclodecanone 
• 52190-38-2 2-(methylthio)cyclododecanone 
• 96-00-4 2-hydroxycyclodecanone 
• 6838-68-2 C₁₆H₃₄O₂Si₂ 
• 830-13-7 cyclododecanone 

Downstream Products

• 140237-55-4 2-(2-Oxoethyl)cyclooctanone 
• 103047-56-9 3,10-dibenzyl-cyclodecane-1,2-dione 
• 116031-37-9 3,10-bis-(3-methyl-benzylidene)-cyclodecane-1,2-dione 
• 103267-81-8 3,10-bis-(4-isopropyl-benzylidene)-cyclodecane-1,2-dione 
• 115293-74-8 3,10-bis-(4-methoxy-benzylidene)-cyclodecane-1,2-dione 
• 102749-07-5 3,10-dibenzylidene-cyclodecane-1,2-dione 
• 101747-32-4 3-benzylidene-cyclodecane-1,2-dione 
• 116030-71-8 3,10-bis-(4-methyl-benzylidene)-cyclodecane-1,2-dione 
• 103264-80-8 3,10-bis-(α-piperidino-benzyl)-cyclodecane-1,2-dione 
• 30572-96-4 cis-cyclodecane-1,2-diol 
• 111-20-6 1,10-decanedioic acid 

Relevant articles and documents

A rapid and convenient synthesis of α-diketones

A novel and simple synthetic method for the preparation of series of α-diketones is reported. Α-Ditrimethylsiloxyenes were obtained from the readily available materials diacids or diesters through acyloin condensation, which was oxidized to α-diketones using bromine as the oxidation reagent in presence of water. The structures of α-diketones were confirmed by IR, MS, 1H NMR.

Photo-irradiation of α-halo carbonyl compounds: A novel synthesis of α-hydroxy- and α,α′-dihydroxyketones

The reaction of α-halo ketones (α-iodocycloalkanones, α-bromocycloalkanones, α-iodo-β-alkoxy esters, and α-iodoacyclicketones) with irradiation under a high-pressure mercury lamp gave the corresponding α-hydroxyketones in good yields. For α-bromoketones, it was found that α-hydroxylation does not occur. However, α-bromoketones were converted into α-hydroxyketones in the presence of KI. In the case of α,α′-diiodo ketones, α,α′-dihydroxyketones, which up to now have scarcely been reported, were obtained. This reaction affords a new, clean and convenient synthetic method for α-hydroxy- and α,α′- dihydroxyketones.

A novel synthesis of α-hydroxy- and α,α′- dihydroxyketone from α-iodo and α,α′-diiodo ketone using photoirradiation

A novel reaction of α-iodo ketone (α-iodocycloalkanone, α-iodo-β-alkoxy ester, and α-iodoacyclicketone) with irradiation under a high-pressure mercury lamp gave the corresponding α-hydroxyketone in good yields. In the case of α,α′- diiodo ketone, α,α′-dihydroxyketone which little has been reported until now was obtained. This reaction affords a new, clean and convenient synthetic method for α-hydroxy- and α,α′- dihydroxyketone.