965-50-4

Basic information

• Product Name: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-
• CAS NO: 965-50-4
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 965-50-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(965-50-4)
• EPA Substance Registry System: Benzenepropanamide, N-(4-methoxyphenyl)-b-oxo-(965-50-4)

Safety Data

• Hazardous Substances Data: 965-50-4(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 104-94-9 4-methoxy-aniline 
• 77092-12-7 6-phenyl-2,2-dimethyl-1,3-dioxin-4-one 
• 55991-67-8 5-phenylfuran-2,3-dione 
• 1074-12-0 phenylglyoxal hydrate 
• 5437-98-9 4'-methoxyacetoacetanilide 
• 5382-38-7 2-cyano-N-(4-methoxyphenyl)acetamide 
• 98-80-6 phenylboronic acid 
• 98-86-2 acetophenone 
• 19226-37-0 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one 
• 10507-69-4 4-methoxybenzohydroxamic acid 

Downstream Products

• 104-94-9 4-methoxy-aniline 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 120243-00-7 2-(4-ethyl-1-piperazinyl)-6-methoxy-4-phenylquinoline 
• 120243-01-8 2-(4-ethyl-1-piperazinyl)-6-hydroxy-4-phenylquinoline 
• 120242-99-1 2-chloro-6-methoxy-4-phenylquinoline 
• 80392-90-1 6-Hydroxy-2-imino-1-(4-methoxy-phenyl)-4-phenyl-1,2-dihydro-pyridine-3-carbonitrile 
• 80392-86-5 2-Hydroxy-6-(4-methoxy-phenylamino)-4-phenyl-nicotinonitrile 
• 80392-82-1 2-{Amino-[6-(4-methoxy-phenylamino)-2-oxo-4-phenyl-2H-pyridin-(3Z)-ylidene]-methyl}-malononitrile 
• 1227-44-7 N,N'-bis(4-methoxyphenyl)urea 
• 98-86-2 acetophenone 
• 57183-51-4 6-methoxy-4-phenyl-1H-quinolin-2-one 
• 120613-10-7 2-(4-diethylamino-2-methyl-phenylimino)-3-oxo-3-phenyl-propionic acid p-anisidide 

Relevant articles and documents

1,4,2-Dioxazol-5-ones as Isocyanate Equivalents: An Efficient Synthesis of 2-Quinolinones via β-Keto Amides

Under thermal conditions, 1,4,2-dioxazol-5-ones are known to undergo decarboxylation followed by Lossen's rearrangement to yield isocyanates. Described herein is the in situ trapping of the resulting isocyanates with carbon nucleophiles to synthesize β-keto amides. Furthermore, a general and mild method for the conversion of the resulting β-keto amides into quinolin-2-ones is reported.

NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF

A class of compounds that bind to fatty acid binding protein (FABP4) and modulate adipocyte metabolism to drive enhanced glucose utilization, as well as pharmaceutical compositions comprising the class of compounds, in combination with a pharmaceutically acceptable diluent or carrier, and optionally, further in combination with a therapeutically active agent, and the use of these compounds in medicine and for the preparation of a medicament in the treatment of disorders acting on the FABP4.

Silver(I)-catalyzed tandem approach to β-oxo amides

A facile and efficient AgI-catalytic approach is reported for the first time to synthesize β-oxo amides from β-oxo esters a with broad substrate scope in good to excellent yields. Crossover and in situ NMR studies confirmed that the reaction occurred through a new pathway and not by the traditional condensation reaction. The key advantages of this method are the readily available starting materials, the air-stable reaction, the simple protocol, and the environmental friendliness. A new, catalytic approach to the synthesis of β-oxo amides from β-oxo esters with a broad substrate scope in good to excellent yields was developed. In situ NMR spectroscopy and crossover experiments confirmed the reaction mechanism.