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972-50-9

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  • (7R,8R,9S,10R,13S,14S,17S)-7,17-dihydroxy-10,13,17-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

    Cas No: 972-50-9

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972-50-9 Usage

Description

(7alpha,17beta)-7,17-dihydroxy-17-methylandrost-4-en-3-one, also known as a steroid derivative, is a hormone naturally produced in the body. It features a 17-methylated androstenedione molecular structure and plays a crucial role in regulating various physiological processes. The 7alpha,17beta configuration denotes the stereochemistry of the compound, while the hydroxyl groups at the 7 and 17 positions suggest its potential for metabolic transformation and hormonal activity.

Uses

Used in Pharmaceutical Applications:
(7alpha,17beta)-7,17-dihydroxy-17-methylandrost-4-en-3-one is used as an intermediate in the synthesis of steroid hormones for its potential pharmaceutical applications. Its natural occurrence and hormonal activity make it a valuable compound in the development of medications targeting hormonal imbalances and related conditions.
Used in Hormone Regulation Research:
This steroid derivative is also utilized in research aimed at understanding the complex mechanisms of hormone regulation within the body. Its role in physiological processes provides insights into the development of therapies for various endocrine disorders.
Used in the Synthesis of Anabolic Steroids:
(7alpha,17beta)-7,17-dihydroxy-17-methylandrost-4-en-3-one is used as a key compound in the synthesis of anabolic steroids, which are often prescribed to promote muscle growth and improve athletic performance, as well as to treat conditions like muscle wasting and osteoporosis.
Used in the Chemical Industry:
In the chemical industry, (7alpha,17beta)-7,17-dihydroxy-17-methylandrost-4-en-3-one may be used as a starting material for the production of other steroidal compounds with various applications, such as in the cosmetics and personal care products sector for their anti-inflammatory and skin-regenerative properties.

Check Digit Verification of cas no

The CAS Registry Mumber 972-50-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,7 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 972-50:
(5*9)+(4*7)+(3*2)+(2*5)+(1*0)=89
89 % 10 = 9
So 972-50-9 is a valid CAS Registry Number.

972-50-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7,17-dihydroxy-10,13,17-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:972-50-9 SDS

972-50-9Upstream product

972-50-9Downstream Products

972-50-9Relevant articles and documents

Application of α- and β-naphthoflavones as monooxygenase inhibitors of Absidia coerulea KCh 93, Syncephalastrum racemosum KCh 105 and Chaetomium sp. KCh 6651 in transformation of 17α-methyltestosterone

Janeczko, Tomasz,Pop?oński, Jaros?aw,Koz?owska, Ewa,Dymarska, Monika,Huszcza, Ewa,Kostrzewa-Sus?ow, Edyta

, p. 178 - 184 (2018/03/26)

In this work, 17α-methyltestosterone was effectively hydroxylated by Absidia coerulea KCh 93, Syncephalastrum racemosum KCh 105 and Chaetomium sp. KCh 6651. A. coerulea KCh 93 afforded 6β-, 12β-, 7α-, 11α-, 15α-hydroxy derivatives with 44%, 29%, 6%, 5% and 9% yields, respectively. S. racemosum KCh 105 afforded 7α-, 15α- and 11α-hydroxy derivatives with yields of 45%, 19% and 17%, respectively. Chaetomium sp. KCh 6651 afforded 15α-, 11α-, 7α-, 6β-, 9α-, 14α-hydroxy and 6β,14α-dihydroxy derivatives with yields of 31%, 20%, 16%, 7%, 5%, 7% and 4%, respectively. 14α-Hydroxy and 6β,14α-dihydroxy derivatives were determined as new compounds. Effect of various sources of nitrogen and carbon in the media on biotransformations were tested, however did not affect the degree of substrate conversion or the composition of the products formed. The addition of α- or β-naphthoflavones inhibited 17α-methyltestosterone hydroxylation but did not change the percentage composition of the resulting products.

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