97371-54-5

Basic information

• Product Name: (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon
• Synonyms: (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon
• CAS NO: 97371-54-5
• Molecular Weight: 230.35
• Mol File: 97371-54-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon(97371-54-5)
• EPA Substance Registry System: (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon(97371-54-5)

Safety Data

• Hazardous Substances Data: 97371-54-5(Hazardous Substances Data)

Upstream product

• 89-79-2 (S)-2-Isopropenyl-5-methyl-cyclohexanol 
• 529-00-0 (S)-isopulegone 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 5949-05-3 (S)-Citronellal 
• 108-86-1 bromobenzene 
• 3391-90-0 (S)-(-)-pulegone 
• 89-82-7 pulegone 
• 100-58-3 phenylmagnesium bromide 
• 205057-17-6 (5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexanone 
• 104870-80-6 (1R,2R,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexanol 
• 104870-75-9 (1S,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)-cyclohexan-1-ol 
• 65253-04-5 (-)-8-phenylmenthol 
• 104870-79-3 (2R,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexanone 
• 105229-96-7 (1R)-8-phenylmenthyl (2S)-2-hydroxy-6-methyl-6-heptenoate 

Downstream Products

• 1330630-35-7 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate 
• 1330630-37-9 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-(N,N-dibenzylamino)butanoate 
• 1330630-42-6 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-(N,N-dibenzylamino)butanoate 
• 1330630-38-0 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-(N-isopropyl-N-benzylamino)butanoate 
• 1330630-43-7 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-(N-isopropyl-N-benzylamino)butanoate 
• 1330630-40-4 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-(N,N-dibenzylamino)-3-phenylpropanoate 
• 1330630-44-8 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-(N,N-dibenzylamino)-3-phenylpropanoate 
• 1330630-41-5 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-(N-isopropyl-N-benzylamino)-3-phenylpropanoate 
• 1330630-45-9 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-(N-isopropyl-N-benzylamino)-3-phenylpropanoate 
• 1330630-47-1 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-aminobutanoate 
• 1330630-48-2 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-amino-3-phenylpropanoate 
• 1330630-53-9 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-(isopropylamino)-3-phenylpropanoate 
• 1330630-49-3 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (R)-3-aminobutanoate 
• 1330630-50-6 (1'R,2'S,5'R)-2'-(2''-phenylpropan-2''-yl)-5'-methylcyclohexyl (S)-3-amino-3-phenylpropanoate 

Relevant articles and documents

Stereoselective cathodic synthesis of 8-substituted (1R,3R,4S)-menthylamines

The electrochemical generation of menthylamines from the corresponding menthone oximes equipped with an additional substituent in position 8 is described. Due to 1,3-diaxial interactions a pronounced diastereoselectivity for the menthylamines is found.

Double asymmetric induction as a mechanistic probe: The doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure α,β-unsaturated esters and enantiopure α,β-unsaturated hydroxamates

The doubly diastereoselective conjugate addition of the antipodes of lithium N-benzyl-N-(α-methylbenzyl)amide to a range of enantiopure α,β-unsaturated esters [derived from Corey's 8-phenylmenthol chiral auxiliary] and enantiopure α,β-unsaturated hydroxamates [derived from our 'chiral Weinreb amide' auxiliary (S)-N-1-(1′-naphthyl)ethyl-O-tert- butylhydroxylamine] has been used as a mechanistic probe to determine the reactive conformations of these acceptors.

A short, efficient synthesis of the chiral auxiliary (+)-8- phenylneomenthol

(+)-8-Phenylneomenthol 2, the structure of which was confirmed by X-ray analysis of its 3,5-dinitrobenzoate, was efficiently prepared from commercially available (-)-8-phenylmenthol 3 by oxidation with the Sarett reagent, followed by L-Selectride reduction of the (+)-8-phenylmenthone 6 thus formed. (C) 2000 Elsevier Science Ltd.