98-15-7 Usage
Description
3-Chlorobenzotrifluoride is a water-white liquid with an odor similar to mothballs. It is a clear, colorless liquid that is insoluble in water and denser than water. It has a flash point between 65-108°F and is toxic by inhalation. Liquid contact may cause irritation to the skin and eyes.
Uses
Used in Organic Synthesis:
3-Chlorobenzotrifluoride is used as an intermediate in organic synthesis for the production of various chemicals.
Used in Pharmaceutical Industry:
3-Chlorobenzotrifluoride is used as an intermediate in the manufacturing of pharmaceuticals, contributing to the development of new drugs and medications.
Used in Agrochemical Industry:
3-Chlorobenzotrifluoride is used as an intermediate in the production of agrochemicals, such as insecticides, to help protect crops and enhance agricultural productivity.
Used in Dye Industry:
3-Chlorobenzotrifluoride is used as an intermediate in the manufacturing of dyes and dyestuff, playing a crucial role in the creation of various colorants for different applications.
Used in Dielectrics:
3-Chlorobenzotrifluoride is utilized as a dielectric material, which is essential in the insulation and functioning of electrical components and systems.
Air & Water Reactions
Highly flammable. On contact with water 3-Chlorobenzotrifluoride can evolve hydrogen fluoride, a highly toxic and corrosive gas. [AAR, 1999]. Insoluble in water and denser than water.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Purification Methods
Purify it as for o-chlorobenzotrifluoride above. 20 1.4432. [Beilstein 5 III 692, 5 IV 814.]
Check Digit Verification of cas no
The CAS Registry Mumber 98-15-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 98-15:
(4*9)+(3*8)+(2*1)+(1*5)=67
67 % 10 = 7
So 98-15-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClF3/c8-6-3-1-2-5(4-6)7(9,10)11/h1-4H
98-15-7Relevant articles and documents
Cathodic C-H Trifluoromethylation of Arenes and Heteroarenes Enabled by an in Situ-Generated Triflyltriethylammonium Complex
Cantillo, David,Jud, Wolfgang,Kappe, C. Oliver,Maljuric, Snjezana
supporting information, (2019/10/08)
While several trifluoromethylation reactions involving the electrochemical generation of CF3 radicals via anodic oxidation have been reported, the alternative cathodic, reductive radical generation has remained elusive. Herein, the first cathodic trifluoromethylation of arenes and heteroarenes is reported. The method is based on the electrochemical reduction of an unstable triflyltriethylammonium complex generated in situ from inexpensive triflyl chloride and triethylamine, which produces CF3 radicals that are trapped by the arenes on the cathode surface.
Copper-mediated trifluoromethylation of diaryliodonium salts with difluoromethyltriflate
Yang, Jing-Yun,Xu, Xiu-Hua,Qing, Feng-Ling
, p. 45 - 51 (2016/05/09)
The reaction of diaryliodonium salts with difluoromethyltriflate in the presence of TBAT and CuTC gave the corresponding trifluoromethylated arenes in moderate yields. Compared to other difluorocarbene-derived trifluoromethylation reactions, the current one proceeded at mild reaction conditions (room temperature) within short reaction time (5 min).
Copper-mediated trifluoromethylation of diaryliodonium salts with TMSCF3 at room temperature
Yang, Jing-Yun,Xu, Xiu-Hua,Qing, Feng-Ling
, p. 175 - 180 (2015/10/20)
A convenient method for the preparation of trifluoromethylated arenes from the reaction of diaryliodonium salts with TMSCF3 in the presence of CuBF4·(MeCN)4 and KF at room temperature within 25 min was developed. This reaction provides a valuable complement to the previously established trifluoromethylation methods.