98-44-2

Basic information

• Product Name: 2-Amino-1,4-benzenedisulfonic acid
• Synonyms: 4-SULFOMETANILIC ACID;ANILINE 2:5 DISULFONIC ACID;ANILINE-2,5-DISULFONIC ACID;ANILINE-2,5-DISULPHONIC ACID;2-AMINO-1,4-BENZENEDISULFONIC ACID;2-AMINO-1,4-DISULFOBENZENE;2-AMINO-P-BENZENEDISULFONIC ACID;2,5-DISULFOANILINE
• CAS NO: 98-44-2
• Molecular Formula: C₆H₇NO₆S₂
• Molecular Weight: 253.25
• EINECS: 202-669-6
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 98-44-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: >300°C
• Boiling Point: 500oC
• Appearance: off-white powder
• Density: 1.569 (estimate)
• Refractive Index: 1.5500 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Aqueous Acid (Slightly), Water (Slightly)
• PKA: -1.15±0.50(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-Amino-1,4-benzenedisulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-1,4-benzenedisulfonic acid(98-44-2)
• EPA Substance Registry System: 2-Amino-1,4-benzenedisulfonic acid(98-44-2)

Safety Data

• Statements: 36/37/38-43
• Safety Statements: 26-36/37/39-36/37
• RTECS: CZ9250000
• TSCA: Yes
• Hazardous Substances Data: 98-44-2(Hazardous Substances Data)

Usage

Description

2-Amino-1,4-benzenedisulfonic acid is an organic compound characterized by its off-white powder form. It is a disulfonated derivative of benzene, featuring an amino group attached to the second carbon and two sulfonic acid groups at the first and fourth carbons. This unique structure endows it with specific chemical properties that make it suitable for various applications, particularly in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
2-Amino-1,4-benzenedisulfonic acid is used as a pharmaceutical intermediate for the synthesis of various drugs and active pharmaceutical ingredients. Its chemical structure allows it to serve as a building block in the development of new medications, contributing to the advancement of healthcare and treatment options.
As a pharmaceutical intermediate, 2-Amino-1,4-benzenedisulfonic acid is utilized for its ability to react with other compounds to form new molecules with potential therapeutic effects. Its presence in the synthesis process can lead to the creation of drugs with improved efficacy, safety, and pharmacokinetic properties.

InChI:InChI=1/C6H7NO6S2/c7-5-3-4(14(8,9)10)1-2-6(5)15(11,12)13/h1-3H,7H2,(H,8,9,10)(H,11,12,13)/p-2

Upstream product

• 121-47-1 3-aminobenzenesulfonic acid 
• 7647-01-0 hydrogenchloride 
• 17691-19-9 4-chloro-3-nitrobenzenesulphonic acid sodium salt 
• 7757-83-7 sodium sulfite 
• 1245707-84-9 C₇H₅NO₃S₂ 

Downstream Products

• 121-47-1 3-aminobenzenesulfonic acid 
• 22185-69-9 C₁₄H₁₅N₃O₇S₂ 
• 69774-80-7 C₁₆H₁₃N₃O₉S₃ 
• 742062-32-4 C₁₁H₁₅N₇O₆S₂ 
• 1059230-60-2 C₁₆H₂₃N₇O₆S₂ 
• 921762-11-0 C₁₅H₂₁N₇O₇S₂ 
• 1059230-62-4 C₁₅H₂₁N₇O₆S₂ 
• 1059230-68-0 C₁₇H₂₆N₈O₆S₂ 
• 1059230-71-5 C₁₈H₂₇N₇O₆S₂ 
• 1059230-75-9 C₁₆H₂₃N₇O₆S₂ 
• 939385-73-6 C₁₃H₁₉N₇O₆S₂ 

Relevant articles and documents

Development of an efficient ruthenium catalyzed synthetic process and mechanism for the facile conversion of benzothiazoles to orthanilic acids

Ruthenium-Schiff base complex catalyzed efficient protocol has been developed for the synthesis of orthanilic acids from benzothiazoles in good to excellent yields using N-haloamines. Hexa-coordinated ruthenium complex with Schiff base and triphenylphosphine ligands has been prepared and its catalytic function was invented for the synthesis of orthanilic acids. The synthetic process utilizes our efficient method for the selective and preferential oxidation of thiazole ring of benzothiazoles using N-haloamines without effecting phenyl ring. The detailed catalytic, mechanistic and kinetic investigations have been made for the synthetic reactions. Solvent isotope studies have been made in H2O-D2O and the reactions were carried out at different temperatures. Under the identical set of conditions, the kinetics of catalyzed reactions has been compared with uncatalyzed reactions and found that the catalyzed reactions are 9-11 folds faster. The catalytic constants (KC) have been calculated for each N-haloamine at different temperatures and the values of activation parameters with respect to the catalyst have been evaluated. Spectroscopic evidence for the formation of 1:1 complex between N-haloamine and ruthenium has been obtained. The observed results have been explained by a plausible mechanism and the related rate law has been deduced.

Process for the preparation of 2-aminobenzene-1,4-disulphonic acids and the new compound 6-chloro-2-aminobenzene-1,4-disulphonic acid

The present invention relates to an improved preparation process for 2-aminobenzene-1,4-disulphonic acids and the new compound 6-chloro-2-aminobenzene-1,4-disulphonic acid.

2,4-diamino-6-fluorotriazine disazo reactive dyestuffs

A dyestuff of the formula STR1 in which R is H or Ch3 STR2 in which R1 is H, substituted or unsubstituted C1 -C4 -alkyl or --X--Y X is a divalent aliphatic, cycloaliphatic, aliphaticcycloaliphatic radical or an araliphatic radical Y is COOH, SO3 H, OSO3 H or SO2 G, in which G is CH=CH2 or --CH2 --CH2 --Z, in which Z denotes a group which can be eliminated under alkaline conditions, R2 is H or C1 -C4 -alkyl, and the benzene radical D and the benzene or naphthalene radical L can contain customary substituents, is suitable for the dyeing and printing of OH- and NH-containing materials. They produce lightfast and wetfast brilliant dyeings and prints.